Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 15/20 | 0.81 |
| ▸ | HTR1D | P28221 | 10/20 | 0.81 |
| ▸ | HTR1B | P28222 | 10/20 | 0.81 |
| ▸ | DRD2 | P14416 | 6/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.53 |
| ▸ | HTR2A | P28223 | 5/20 | 0.53 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9058789 | 0.89 | HTR1A (0.80) | HTR1AHTR1DHTR1BDRD2KCNH2 | |
| SCHEMBL9062634 | 0.88 | HTR1A (0.81) | HTR1AHTR1DHTR1BDRD2KCNH2 | |
| SCHEMBL9054738 | 0.88 | HTR1A (0.81) | HTR1AHTR1DHTR1BDRD2KCNH2 | |
| SCHEMBL9058567 | 0.86 | HTR1A (0.74) | HTR1AHTR1DHTR1BDRD2KCNH2 | |
| SCHEMBL9057945 | 0.84 | HTR1A (0.74) | HTR1AHTR1DHTR1BDRD2KCNH2 | |
| SCHEMBL9057938 | 0.83 | HTR1A (0.66) | HTR1AHTR1DHTR1BDRD2KCNH2 | |
| SCHEMBL9058518 | 0.83 | HTR1A (0.66) | HTR1AHTR1DHTR1BDRD2DRD3 | |
| SCHEMBL9058797 | 0.82 | HTR1A (0.67) | HTR1AHTR1DHTR1BDRD2KCNH2 | |
| SCHEMBL8187450 | 0.80 | HTR1A (0.71) | HTR1AHTR1DHTR1BDRD2KCNH2 | |
| SCHEMBL9059019 | 0.80 | HTR1A (0.64) | HTR1AHTR1DHTR1BDRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996012713-A1 | NOVEL NAPHTHYLPIPERAZINE-DERIVED AROMATIC ETHERS FOR USE AS DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1996-05-02 | — | — | WO | claimed |
| WO-1996012713-A1 | NOVEL NAPHTHYLPIPERAZINE-DERIVED AROMATIC ETHERS FOR USE AS DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1996-05-02 | — | — | WO | disclosed |