Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14773591 | 0.87 | TP53 (0.52) | TP53CYP3A4KAT6AALDH1A1SMN1; SMN2 | |
| SCHEMBL13592998 | 0.87 | TP53 (0.52) | TP53CYP3A4KAT6AALDH1A1SMN1; SMN2 | |
| SCHEMBL5610156 | 0.85 | KAT6A (0.51) | TP53CYP3A4KAT6AALDH1A1SMN1; SMN2 | |
| SCHEMBL3283827 | 0.85 | TP53 (0.50) | TP53CYP3A4KAT6AALDH1A1SMN1; SMN2 | |
| SCHEMBL29469874 | 0.85 | CA1 (0.62) | TP53CYP3A4KAT6AKDM4ETSHR | |
| SCHEMBL5610159 | 0.85 | CA1 (0.62) | TP53CYP3A4KAT6AKDM4ETSHR | |
| SCHEMBL3492741 | 0.85 | KAT6A (0.51) | TP53CYP3A4KAT6AALDH1A1SMN1; SMN2 | |
| SCHEMBL24686632 | 0.84 | KAT6A (0.50) | TP53CYP3A4KAT6AALDH1A1SMN1; SMN2 | |
| SCHEMBL28236411 | 0.84 | TP53 (0.49) | TP53CYP3A4KAT6ANAMPTALDH1A1 | |
| SCHEMBL13588821 | 0.82 | TP53 (0.47) | TP53CYP3A4KAT6AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491661-B1 | Process for the hydrophilization of contact lenses | CIBA GEIGY AG (CH) | 1996-09-25 | — | — | EP | disclosed |
| US-5408280-A | Process for rendering contact lenses hydrophilic | CIBA-GEIGY CORPORATION (US) | 1995-04-18 | — | — | US | disclosed |
| EP-0491661-A2 | Process for the hydrophilization of contact lenses | CIBA-GEIGY AG (CH) | 1992-06-24 | — | — | EP | disclosed |