Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 10/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9059005 | 1.00 | RECQL (0.57) | RECQLMAPTLMNARAB9AHPGD | |
| SCHEMBL11465588 | 0.85 | MAPT (0.59) | RECQLMAPTLMNARAB9AHPGD | |
| SCHEMBL801553 | 0.85 | MAPT (0.59) | RECQLMAPTLMNARAB9AHPGD | |
| SCHEMBL6624771 | 0.84 | MAPT (0.59) | RECQLMAPTLMNARAB9AHPGD | |
| SCHEMBL14254338 | 0.79 | MAPT (0.54) | RECQLMAPTLMNARAB9AHPGD | |
| SCHEMBL4894903 | 0.79 | RECQL (0.75) | RECQLMAPTLMNARAB9AHPGD | |
| SCHEMBL4894896 | 0.79 | RECQL (0.75) | RECQLMAPTLMNARAB9AHPGD | |
| SCHEMBL23251385 | 0.78 | MAPT (0.81) | RECQLMAPTLMNARAB9AHPGD | |
| SCHEMBL16627905 | 0.78 | MAPT (0.78) | RECQLMAPTLMNARAB9AHPGD | |
| SCHEMBL16911749 | 0.78 | MAPT (0.78) | RECQLMAPTLMNARAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |