SCHEMBL16627905

SCHEMBL16627905

COc1ccc(C(=O)/C=C/N(C)C)cc1C

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.78
▸ LMNA P02545 3/20 0.78
▸ ALDH1A1 P00352 7/20 0.60
▸ HPGD P15428 3/20 0.60
▸ RAB9A P51151 4/20 0.52
▸ KMT2A Q03164 3/20 0.52
▸ POLB P06746 2/20 0.52
▸ MEN1 O00255 2/20 0.52
▸ CYP1A2 P05177 2/20 0.51
▸ CYP2C19 P33261 2/20 0.51
▸ RECQL P46063 2/20 0.51
▸ ALOX12 P18054 1/20 0.51
▸ ABCG2 Q9UNQ0 3/20 0.50
▸ HTT P42858 2/20 0.50
▸ GAA P10253 1/20 0.50
▸ NPC1 O15118 2/20 0.49
▸ HSP90AA1 P07900 1/20 0.49
▸ SMN1; SMN2 Q16637 1/20 0.49
▸ ABCB1 P08183 1/20 0.47
▸ TNFRSF1A P19438 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16911749 1.00 MAPT (0.78) MAPTLMNAALDH1A1HPGDRAB9A
SCHEMBL15777949 0.88 MAPT (0.78) MAPTLMNAALDH1A1HPGDRAB9A
SCHEMBL801281 0.88 MAPT (0.78) MAPTLMNAALDH1A1HPGDRAB9A
SCHEMBL783250 0.88 MAPT (1.00) MAPTLMNAALDH1A1HPGDRAB9A
SCHEMBL805341 0.88 MAPT (1.00) MAPTLMNAALDH1A1HPGDRAB9A
SCHEMBL16911072 0.84 MAPT (0.59) MAPTLMNAALDH1A1HPGDRAB9A
SCHEMBL3606868 0.84 MAPT (0.76) MAPTLMNAALDH1A1HPGDRAB9A
SCHEMBL16911346 0.84 MAPT (0.76) MAPTLMNAALDH1A1HPGDRAB9A
SCHEMBL3606864 0.84 MAPT (0.76) MAPTLMNAALDH1A1HPGDRAB9A
SCHEMBL16920749 0.84 MAPT (0.76) MAPTLMNAALDH1A1HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3020715-B1 TETRAZOLINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2021-06-16 — — EP disclosed
US-9888688-B2 Tetrazolinone compounds and applications thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-13 — — US disclosed
US-9888688-B2 Tetrazolinone compounds and applications thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-13 — — US disclosed
US-9828389-B2 Tetrazolinone compounds and their use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-28 — — US disclosed
US-9826741-B2 Tetrazolinone compound and application thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-28 — — US disclosed
US-9828389-B2 Tetrazolinone compounds and their use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-28 — — US disclosed
EP-2900654-B1 TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2017-05-17 — — EP disclosed
EP-2900655-B1 TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2017-05-10 — — EP disclosed
US-20170105415-A1 TETRAZOLINONE COMPOUND AND APPLICATION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-04-20 — — US disclosed
US-20170105415-A1 TETRAZOLINONE COMPOUND AND APPLICATION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-04-20 — — US disclosed
US-20160150787-A1 TETRAZOLINONE COMPOUNDS AND APPLICATIONS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-06-02 — — US disclosed
US-20160150787-A1 TETRAZOLINONE COMPOUNDS AND APPLICATIONS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-06-02 — — US disclosed
US-9314023-B2 Tetrazolinone compounds and their use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-04-19 — — US disclosed
US-9314023-B2 Tetrazolinone compounds and their use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-04-19 — — US disclosed
WO-2015147332-A1 TETRAZOLINONE COMPOUND AND APPLICATION FOR SAME 住友化学株式会社 2015-10-01 — — WO disclosed
US-20150223460-A1 TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-08-13 — — US disclosed
US-20150223460-A1 TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-08-13 — — US disclosed
US-20150203511-A1 TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-07-23 — — US disclosed
US-20150203511-A1 TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-07-23 — — US disclosed
WO-2015050040-A1 PLANT DISEASE CONTROL COMPOSITION AND USE THEREOF 住友化学株式会社 2015-04-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150223460-A1 TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES CYCS, MT-CO3, OXER1 MAPT 4050/4885LMNA 4091/4885ALDH1A1 1942/4885
US-20160150787-A1 TETRAZOLINONE COMPOUNDS AND APPLICATIONS THEREOF SOD1, UQCRB, MT-CO1 MAPT 3902/4885LMNA 3901/4885ALDH1A1 1192/4885
US-20150203511-A1 TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES CYCS, MT-CO3, CYP4F11 MAPT 4034/4885LMNA 3709/4885ALDH1A1 1436/4885
US-20170105415-A1 TETRAZOLINONE COMPOUND AND APPLICATION THEREOF KCNK4, CASP4, KCNA4 MAPT 4009/4885LMNA 4078/4885ALDH1A1 1096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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