Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.52 |
| ▸ | NTSR2 | O95665 | 9/20 | 0.48 |
| ▸ | NTSR1 | P30989 | 9/20 | 0.48 |
| ▸ | ACE | P12821 | 5/20 | 0.46 |
| ▸ | REN | P00797 | 2/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9059237 | 1.00 | OPRK1 (0.52) | OPRK1NTSR2NTSR1ACEREN | |
| SCHEMBL29524168 | 0.93 | OPRK1 (0.53) | OPRK1NTSR2NTSR1ACESORT1 | |
| SCHEMBL30434949 | 0.90 | ACE (0.55) | OPRK1ACEREN | |
| SCHEMBL29501732 | 0.90 | ACE (0.52) | ACEREN | |
| SCHEMBL30460477 | 0.88 | OPRK1 (0.53) | OPRK1NTSR2NTSR1ACESORT1 | |
| SCHEMBL6660498 | 0.88 | ACE (0.47) | ACEREN | |
| SCHEMBL38659667 | 0.87 | OPRK1 (0.48) | OPRK1NTSR2NTSR1ACEREN | |
| SCHEMBL30434892 | 0.87 | ACE (0.52) | OPRK1ACEREN | |
| SCHEMBL30844025 | 0.86 | ACE (0.46) | OPRK1NTSR2NTSR1ACEREN | |
| SCHEMBL29409430 | 0.86 | OPRK1 (0.55) | OPRK1NTSR2NTSR1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996018646-A2 | HEAT SHOCK PROTEIN PEPTIDES AND METHODS FOR MODULATING AUTOIMMUNE CENTRAL NERVOUS SYSTEM DISEASE | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1996-06-20 | — | — | WO | disclosed |