Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 2/20 | 0.32 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL561442 | 0.95 | — | — | |
| SCHEMBL2194813 | 0.77 | CRBN (0.44) | CRBNEPHX2TOP2ATOP2BALDH1A1 | |
| Formaldehyde SCHEMBL8835722 | 0.77 | CRBN (0.44) | CRBNEPHX2TOP2ATOP2BALDH1A1 | |
| SCHEMBL9173145 | 0.77 | CRBN (0.41) | CRBNDDB1 | |
| SCHEMBL9193306 | 0.77 | CRBN (0.33) | CRBN | |
| SCHEMBL5235519 | 0.76 | — | — | |
| SCHEMBL28402591 | 0.76 | — | — | |
| SCHEMBL8999579 | 0.75 | CRBN (0.46) | CRBNEPHX2TOP2ATOP2BALDH1A1 | |
| SCHEMBL10963440 | 0.74 | CRBN (0.46) | CRBNEPHX2TOP2ATOP2BALDH1A1 | |
| Formaldehyde SCHEMBL8154211 | 0.74 | CYP3A4 (0.38) | CRBNEPHX2TOP2ATOP2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1064813-C | Hydroxymethyl hydantoin compositions | LONZA AG (US) | 2001-04-25 | — | — | CN | disclosed |
| EP-0571903-B1 | A method for preparing low free formaldehyde methylol-hydantoins and compositions thereof | LONZA AG (US) | 1996-08-28 | — | — | EP | disclosed |
| US-5405862-A | Microbiocides | LONZA INC. (US) | 1995-04-11 | — | — | US | disclosed |
| EP-0571903-A1 | A method for preparing low free formaldehyde methylol-hydantoins and compositions thereof | LONZA INC. (US) | 1993-12-01 | — | — | EP | disclosed |