Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TOP2A | P11388 | 2/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL191785 | 0.95 | — | — | |
| Ammonia Solution, Strong SCHEMBL28261588 | 0.93 | CRBN (0.46) | CRBNMAPTTOP2ATOP2BALDH1A1 | |
| Methylene Chloride SCHEMBL27573008 | 0.89 | CRBN (0.43) | CRBNMAPTTOP2ATOP2BALDH1A1 | |
| Propionamide SCHEMBL27792957 | 0.82 | CRBN (0.38) | CRBNMAPTTOP2ATOP2BALDH1A1 | |
| SCHEMBL14401319 | 0.80 | — | — | |
| SCHEMBL6791013 | 0.79 | MAPT (0.38) | CRBNMAPTALDH1A1LMNAEPHX2 | |
| Formaldehyde SCHEMBL9059280 | 0.77 | CRBN (0.39) | CRBNMAPTTOP2ATOP2BALDH1A1 | |
| SCHEMBL193400 | 0.77 | CRBN (0.50) | CRBNMAPTTOP2ATOP2BALDH1A1 | |
| SCHEMBL14401321 | 0.77 | — | — | |
| SCHEMBL5235519 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681381-A | POSTAGE METERING SYSTEM | PITNEY BOWES INC. (US) | 1997-10-28 | — | — | US | claimed |