⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11167857 | 1.00 | — | — | |
| SCHEMBL18597612 | 1.00 | — | — | |
| Bromide SCHEMBL28821481 | 0.97 | — | — | |
| Sulfuric Acid SCHEMBL11556963 | 0.90 | NOS1 (0.40) | — | |
| Sulfuric Acid SCHEMBL11556961 | 0.90 | NOS1 (0.40) | — | |
| SCHEMBL26737363 | 0.79 | NOS1 (0.50) | — | |
| SCHEMBL26695793 | 0.79 | NOS1 (0.50) | — | |
| SCHEMBL1920671 | 0.78 | — | — | |
| SCHEMBL1920670 | 0.78 | — | — | |
| SCHEMBL18068279 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012130803-A1 | METHOD FOR SEPARATING OFF HALOGENS FROM MIXTURES OF MATTER | BAYER TECHNOLOGY SERVICES GMBH (DE) | 2012-10-04 | — | — | WO | claimed |
| EP-0385038-B1 | ORTHO-SUBSTITUTED PHENYL AMIDINE AND PHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | The Boots Company PLC (GB) | 1993-06-02 | — | — | EP | claimed |
| EP-0385038-A1 | Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them | The Boots Company PLC (GB) | 1990-09-05 | — | — | EP | claimed |
| EP-0030835-B1 | DERIVATIVES OF 2-SUBSTITUTED-6-PHENYL-3(2H)PYRIDAZINONE, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MORISHITA PHARMACEUTICAL CO. LTD. (JP) | 1983-05-11 | — | — | EP | claimed |
| EP-0030835-A1 | Derivatives of 2-substituted-6-phenyl-3(2H)pyridazinone, their production and pharmaceutical compositions containing them | MORISHITA PHARMACEUTICAL CO. LTD. (JP) | 1981-06-24 | — | — | EP | claimed |
| US-20220267379-A1 | NOVEL INHIBITORS OF KALLIKREIN PROTEASES AND USES THEREOF | UNIVERSITÉ PARIS CITÉ (FR) | 2022-08-25 | — | — | US | disclosed |
| CN-103755709-B | The microwave assistant preparation method of sildenafil derivative | GUANGDONG PHARMACEUTICAL UNIVERSITY (CN) | 2016-05-25 | — | — | CN | disclosed |
| CN-103755709-A | Microwave-assisted preparation method of sildenafil derivatives | UNIV GUANGDONG PHARM | 2014-04-30 | — | — | CN | disclosed |
| WO-1996017612-A1 | USE OF SUBSTITUTED PHENYLAMIDINE AND PHENYLGUANIDINE COMPOUNDS FOR THE TREATMENT OF CEREBRAL AND CARDIAC ISCHAEMIA, CONVULSION AND SICKLE CELL ANAEMIA | KNOLL AKTIENGESELLSCHAFT (DE) | 1996-06-13 | — | — | WO | disclosed |
| US-5373008-A | Phenylamidine and phenylguanidine derivatives and their use as anti-diabetic agents | THE BOOTS COMPANT PLC. (GB) | 1994-12-13 | — | — | US | disclosed |
| US-5223498-A | Hypoglycemic agents | THE BOOTS COMPANY PLC (GB) | 1993-06-29 | — | — | US | disclosed |
| EP-0385038-B1 | ORTHO-SUBSTITUTED PHENYL AMIDINE AND PHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | The Boots Company PLC (GB) | 1993-06-02 | — | — | EP | disclosed |
| EP-0385038-A1 | Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them | The Boots Company PLC (GB) | 1990-09-05 | — | — | EP | disclosed |
| US-4070475-A | THIOALKYL-, AMINOALKYL-, AND OXYALKYL- SUBSTITUTED GUANIDINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1978-01-24 | — | — | US | disclosed |