⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8419378 | 0.84 | — | — | |
| SCHEMBL7626788 | 0.73 | — | — | |
| SCHEMBL9460678 | 0.73 | — | — | |
| SCHEMBL790897 | 0.69 | — | — | |
| SCHEMBL17138405 | 0.69 | — | — | |
| SCHEMBL482836 | 0.68 | — | — | |
| SCHEMBL9345643 | 0.67 | — | — | |
| SCHEMBL8668151 | 0.67 | — | — | |
| SCHEMBL29233067 | 0.65 | — | — | |
| SCHEMBL8745314 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0683782-A4 | SPIRO (2H-1-BENZOPYRAN-2, 4' PIPERIDINE) CLASS III ANTIARRHYTHMICS. | MERCK & CO INC (US) | 1996-03-27 | — | — | EP | disclosed |
| EP-0683782-A1 | SPIRO (2H-1-BENZOPYRAN-2, 4' PIPERIDINE) CLASS III ANTIARRHYTHMICS | MERCK & CO. INC. (US) | 1995-11-29 | — | — | EP | disclosed |
| WO-1994018204-A1 | SPIRO (2H-1-BENZOPYRAN-2, 4' PIPERIDINE) CLASS III ANTIARRHYTHMICS | MERCK & CO., INC. (US) | 1994-08-18 | — | — | WO | disclosed |