Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9424131 | 0.86 | POLB (0.47) | LMNAGAAMCOLN3KMT2ANPC1 | |
| SCHEMBL9424584 | 0.82 | KMT2A (0.41) | LMNAGAAMCOLN3KMT2ANPC1 | |
| SCHEMBL9059942 | 0.76 | ALDH1A1 (0.59) | LMNAGAAMCOLN3KMT2ANPC1 | |
| SCHEMBL9555520 | 0.76 | ALDH1A1 (0.40) | LMNAGAAMCOLN3KMT2ANPC1 | |
| Iodide SCHEMBL9423992 | 0.75 | ALDH1A1 (0.39) | LMNAGAAMCOLN3KMT2ANPC1 | |
| SCHEMBL9059090 | 0.70 | POLB (0.44) | LMNAKMT2ANPC1ALDH1A1POLB | |
| SCHEMBL9424727 | 0.69 | ALDH1A1 (0.56) | LMNAGAAMCOLN3KMT2AALDH1A1 | |
| Iodide SCHEMBL9423963 | 0.68 | ALDH1A1 (0.55) | LMNAGAAMCOLN3KMT2AALDH1A1 | |
| SCHEMBL9064067 | 0.68 | KMT2A (0.55) | KMT2ARAB9AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9059191 | 0.67 | SMN1; SMN2 (0.47) | GAAKMT2ANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996017612-A1 | USE OF SUBSTITUTED PHENYLAMIDINE AND PHENYLGUANIDINE COMPOUNDS FOR THE TREATMENT OF CEREBRAL AND CARDIAC ISCHAEMIA, CONVULSION AND SICKLE CELL ANAEMIA | KNOLL AKTIENGESELLSCHAFT (DE) | 1996-06-13 | — | — | WO | disclosed |