Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9059853 | 1.00 | GAA (0.35) | GAAL3MBTL1DRD3DRD2HTR2A | |
| SCHEMBL9059919 | 0.87 | SMN1; SMN2 (0.41) | GAAL3MBTL1DRD3DRD2LMNA | |
| SCHEMBL9059917 | 0.87 | SMN1; SMN2 (0.41) | GAAL3MBTL1DRD3DRD2LMNA | |
| SCHEMBL9059509 | 0.83 | GAA (0.39) | GAAL3MBTL1PKMBCHELMNA | |
| SCHEMBL9059323 | 0.80 | SMN1; SMN2 (0.44) | GAAL3MBTL1DRD3DRD2PKM | |
| SCHEMBL9059862 | 0.78 | POLB (0.37) | GAAL3MBTL1HTR2AHTR2CSLC6A4 | |
| SCHEMBL9059813 | 0.75 | SMN1; SMN2 (0.40) | GAAL3MBTL1DRD3DRD2PKM | |
| SCHEMBL9059083 | 0.73 | SOAT1 (0.38) | DRD3DRD2LMNAALDH1A1 | |
| SCHEMBL9059080 | 0.73 | SOAT1 (0.38) | DRD3DRD2LMNAALDH1A1 | |
| SCHEMBL9059648 | 0.71 | AKR1C3 (0.44) | L3MBTL1LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996017612-A1 | USE OF SUBSTITUTED PHENYLAMIDINE AND PHENYLGUANIDINE COMPOUNDS FOR THE TREATMENT OF CEREBRAL AND CARDIAC ISCHAEMIA, CONVULSION AND SICKLE CELL ANAEMIA | KNOLL AKTIENGESELLSCHAFT (DE) | 1996-06-13 | — | — | WO | claimed |
| WO-1996017612-A1 | USE OF SUBSTITUTED PHENYLAMIDINE AND PHENYLGUANIDINE COMPOUNDS FOR THE TREATMENT OF CEREBRAL AND CARDIAC ISCHAEMIA, CONVULSION AND SICKLE CELL ANAEMIA | KNOLL AKTIENGESELLSCHAFT (DE) | 1996-06-13 | — | — | WO | disclosed |