Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9059919 | 0.93 | SMN1; SMN2 (0.41) | SMN1; SMN2HTTL3MBTL1DRD2DRD3 | |
| SCHEMBL9059917 | 0.93 | SMN1; SMN2 (0.41) | SMN1; SMN2HTTL3MBTL1DRD2DRD3 | |
| SCHEMBL9059813 | 0.92 | SMN1; SMN2 (0.40) | SMN1; SMN2HTTL3MBTL1DRD2DRD3 | |
| SCHEMBL9059822 | 0.87 | SMN1; SMN2 (0.46) | SMN1; SMN2HTTL3MBTL1DRD2DRD3 | |
| SCHEMBL9059818 | 0.87 | SMN1; SMN2 (0.46) | SMN1; SMN2HTTL3MBTL1DRD2DRD3 | |
| SCHEMBL9424111 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1DRD2DRD3GAA | |
| SCHEMBL9424109 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1DRD2DRD3GAA | |
| SCHEMBL9555559 | 0.81 | L3MBTL1 (0.39) | SMN1; SMN2HTTL3MBTL1GAAALDH1A1 | |
| SCHEMBL9059908 | 0.81 | ALDH1A1 (0.41) | SMN1; SMN2HTTL3MBTL1GAAALDH1A1 | |
| SCHEMBL9555562 | 0.81 | L3MBTL1 (0.39) | SMN1; SMN2HTTL3MBTL1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996017612-A1 | USE OF SUBSTITUTED PHENYLAMIDINE AND PHENYLGUANIDINE COMPOUNDS FOR THE TREATMENT OF CEREBRAL AND CARDIAC ISCHAEMIA, CONVULSION AND SICKLE CELL ANAEMIA | KNOLL AKTIENGESELLSCHAFT (DE) | 1996-06-13 | — | — | WO | claimed |
| WO-1996017612-A1 | USE OF SUBSTITUTED PHENYLAMIDINE AND PHENYLGUANIDINE COMPOUNDS FOR THE TREATMENT OF CEREBRAL AND CARDIAC ISCHAEMIA, CONVULSION AND SICKLE CELL ANAEMIA | KNOLL AKTIENGESELLSCHAFT (DE) | 1996-06-13 | — | — | WO | disclosed |