Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSPO | P30536 | 1/20 | 0.51 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287064 | 0.88 | OPRK1 (0.76) | OPRK1LMNAPDE3APDE4DHTR2B | |
| SCHEMBL11339291 | 0.88 | OPRK1 (0.76) | OPRK1LMNAPDE3APDE4DHTR2B | |
| SCHEMBL11284788 | 0.88 | OPRK1 (0.76) | OPRK1LMNAPDE3APDE4DHTR2B | |
| SCHEMBL10193351 | 0.86 | OPRK1 (0.60) | OPRK1LMNAPDE3APDE4DHTR2B | |
| SCHEMBL9059857 | 0.85 | OPRK1 (0.47) | OPRK1LMNAPDE3APDE4DHTR2B | |
| SCHEMBL9061591 | 0.81 | OPRK1 (0.44) | OPRK1LMNAPDE3APDE4DHTR2B | |
| SCHEMBL11964613 | 0.80 | OPRK1 (0.62) | OPRK1LMNAPDE3APDE4DHTR2B | |
| SCHEMBL607292 | 0.80 | OPRK1 (0.53) | OPRK1LMNAPDE3APDE4DHTR2B | |
| SCHEMBL608162 | 0.80 | OPRK1 (0.53) | OPRK1LMNAPDE3APDE4DHTR2B | |
| SCHEMBL2266031 | 0.80 | OPRK1 (0.55) | OPRK1LMNAPDE3APDE4DHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288514-A | Linking a protected 2-aminobenzophenone to a substrate; deprotecting and reacting with an amino acid; cyclization; removal from substrate; screening | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-02-22 | — | — | US | claimed |
| US-5545568-A | ARRAY OF COMPOUNDS ON SUBSTRATE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-08-13 | — | — | US | disclosed |
| US-5288514-A | Linking a protected 2-aminobenzophenone to a substrate; deprotecting and reacting with an amino acid; cyclization; removal from substrate; screening | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-02-22 | — | — | US | disclosed |