Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21653604 | 0.77 | CA1 (0.57) | CA1CA2KDM4EMEN1KMT2A | |
| SCHEMBL30223611 | 0.77 | HTR2A (0.67) | CA1CA2KDM4EMEN1KMT2A | |
| SCHEMBL8572018 | 0.77 | CA1 (0.57) | CA1CA2KDM4EMEN1KMT2A | |
| SCHEMBL3927394 | 0.77 | HTR2A (0.67) | CA1CA2KDM4EMEN1KMT2A | |
| SCHEMBL11755532 | 0.77 | CA1 (0.62) | CA1CA2KDM4EMEN1KMT2A | |
| SCHEMBL15307679 | 0.76 | HTR2A (0.65) | CA1CA2KDM4EMEN1KMT2A | |
| SCHEMBL21538077 | 0.76 | CA1 (0.58) | CA1CA2KDM4EMEN1KMT2A | |
| SCHEMBL20468978 | 0.76 | CA1 (0.58) | CA1CA2KDM4EMEN1KMT2A | |
| SCHEMBL16291047 | 0.75 | MEN1 (0.63) | CA1CA2KDM4EMEN1KMT2A | |
| SCHEMBL30579465 | 0.75 | MEN1 (0.63) | CA1CA2KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8157475-A | — | — | None | — | — | JP | disclosed |
| JP-H08157475-A | 1-HYDROXYINDOLE DERIVATIVE | KISSEI PHARMACEUT CO LTD | 1996-06-18 | — | — | JP | disclosed |