Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20710996 | 0.92 | MAPT (0.47) | ALDH1A1ROCK2ROCK1TNFRSF1AMAPT | |
| SCHEMBL7682529 | 0.86 | ALDH1A1 (0.61) | ALDH1A1ROCK2ROCK1MAOBMAPT | |
| SCHEMBL26691690 | 0.84 | TYR (0.53) | MAPTMEN1KMT2APTPN1GAA | |
| SCHEMBL6599376 | 0.84 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1KMT2APTPN1 | |
| SCHEMBL6510637 | 0.83 | ALDH1A1 (0.58) | ALDH1A1ROCK2ROCK1MAPTMEN1 | |
| SCHEMBL14455033 | 0.83 | PSEN1 (0.42) | ALDH1A1MAPTMEN1KMT2APTPN1 | |
| SCHEMBL30087228 | 0.83 | PSEN1 (0.42) | ALDH1A1MAPTMEN1KMT2APTPN1 | |
| SCHEMBL3292757 | 0.82 | ALDH1A1 (0.63) | ALDH1A1ROCK2ROCK1MAOBMAPT | |
| SCHEMBL29669441 | 0.82 | ALDH1A1 (0.63) | ALDH1A1ROCK2ROCK1MAOBMAPT | |
| SCHEMBL14501962 | 0.81 | TNFRSF1A (0.45) | ALDH1A1TNFRSF1AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550215-A | FORMING POLYMER ON SUBSTRATE WITH A TETHER MOLECULE; CYCLIZATION; DEPROTECTING; DECYCLIZATION | AFFYMETRIX, INC. | 1996-08-27 | — | — | US | disclosed |
| WO-1993010161-A1 | POLYMER REVERSAL ON SOLID SURFACES | AFFYMAX TECHNOLOGIES N.V. (AN) | 1993-05-27 | — | — | WO | disclosed |