SCHEMBL9060249

SCHEMBL9060249

CCCCC1CCC(c2ccc(-c3ccc(OC(F)(F)F)cc3)cc2)CC1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.43
KDM1A O60341 2/20 0.42
RCOR1 Q9UKL0 1/20 0.42
CYP2C9 P11712 1/20 0.41
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
MEN1 O00255 1/20 0.39
MAPK1 P28482 1/20 0.39
KMT2A Q03164 1/20 0.39
SCN9A Q15858 1/20 0.39
HDAC3 O15379 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC2 Q92769 1/20 0.38
ESR2 Q92731 1/20 0.37
GRM2 Q14416 1/20 0.37
KIF11 P52732 1/20 0.37
HRH2 P25021 1/20 0.37
HRH1 P35367 1/20 0.37
MAOB P27338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9060242 1.00 L3MBTL1 (0.43) L3MBTL1KDM1ARCOR1CYP2C9ALDH1A1
SCHEMBL4801515 0.96 L3MBTL1 (0.42) L3MBTL1KDM1ARCOR1CYP2C9ALDH1A1
SCHEMBL4801521 0.96 L3MBTL1 (0.42) L3MBTL1KDM1ARCOR1CYP2C9ALDH1A1
SCHEMBL8407553 0.96 KDM1A (0.45) L3MBTL1KDM1ARCOR1CYP2C9ALDH1A1
SCHEMBL9061117 0.96 KDM1A (0.45) L3MBTL1KDM1ARCOR1CYP2C9ALDH1A1
SCHEMBL9061970 0.95 L3MBTL1 (0.41) L3MBTL1KDM1ARCOR1CYP2C9ALDH1A1
SCHEMBL9060956 0.95 L3MBTL1 (0.41) L3MBTL1KDM1ARCOR1CYP2C9ALDH1A1
SCHEMBL9061963 0.95 L3MBTL1 (0.41) L3MBTL1KDM1ARCOR1CYP2C9ALDH1A1
SCHEMBL9062448 0.95 L3MBTL1 (0.41) L3MBTL1KDM1ARCOR1CYP2C9ALDH1A1
SCHEMBL10533664 0.95 L3MBTL1 (0.41) L3MBTL1KDM1ARCOR1CYP2C9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9994769-B2 Liquid crystal composition SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO, LTD. (CN) 2018-06-12 US disclosed
US-9994769-B2 Liquid crystal composition SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO, LTD. (CN) 2018-06-12 US disclosed
US-20170015906-A1 LIQUID CRYSTAL COMPOSITION SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO, LTD. (CN) 2017-01-19 US disclosed
US-20170015906-A1 LIQUID CRYSTAL COMPOSITION SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO, LTD. (CN) 2017-01-19 US disclosed
US-9222023-B2 Liquid crystal composition and display device thereof JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2015-12-29 US disclosed
US-20150076405-A1 LIQUID CRYSTAL COMPOSITION AND DISPLAY DEVICE THEREOF JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2015-03-19 US disclosed
US-5536442-A ELECTROOPTICS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1996-07-16 US disclosed
US-5324449-A Substituted phenyl trifluoromethyl ethers MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-06-28 US disclosed