Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | RARB | P10826 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9060176 | 1.00 | RAB9A (0.55) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL9061331 | 1.00 | RAB9A (0.55) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL9061223 | 1.00 | RAB9A (0.55) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL9060672 | 1.00 | RAB9A (0.55) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL9061875 | 0.99 | RAB9A (0.56) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL9061410 | 0.96 | NPC1 (0.59) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL9061720 | 0.90 | RAB9A (0.51) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL9511824 | 0.89 | RAB9A (0.52) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL9512451 | 0.89 | RAB9A (0.52) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL9513305 | 0.88 | RAB9A (0.54) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536442-A | ELECTROOPTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-16 | — | — | US | disclosed |
| US-5389292-A | Liquid crystalline media having positive dielctric anisotropy, chemical, heat and radiation resistance, used as electro-optical displaying | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-14 | — | — | US | disclosed |