Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL273486 | 0.83 | TDP1 (0.52) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL9060998 | 0.82 | TDP1 (0.48) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL4394556 | 0.82 | ASAH1 (0.49) | TDP1HTTLMNASMN1; SMN2ASAH1 | |
| SCHEMBL4075893 | 0.82 | ASAH1 (0.49) | TDP1HTTLMNASMN1; SMN2ASAH1 | |
| SCHEMBL3805246 | 0.79 | TDP1 (0.42) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL16402072 | 0.78 | MEN1 (0.42) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL8792548 | 0.76 | TDP1 (0.46) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL6381049 | 0.76 | TDP1 (0.48) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL8013907 | 0.75 | TDP1 (0.52) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL8412995 | 0.74 | MEN1 (0.47) | TDP1CYP11B1CYP11B2TNFHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015009699-A1 | METHODS AND COMPOSITIONS TO PREVENT OR TREAT BACTERIAL INFECTIONS | KETTER PATRICK (US) | 2015-01-22 | — | — | WO | disclosed |