Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9061255 | 1.00 | HTT (0.45) | HTTKMT2ASMN1; SMN2TDP1POLB | |
| SCHEMBL9061276 | 1.00 | HTT (0.45) | HTTKMT2ASMN1; SMN2TDP1POLB | |
| SCHEMBL9061601 | 0.96 | HTT (0.49) | HTTKMT2ASMN1; SMN2TDP1POLB | |
| SCHEMBL9061608 | 0.96 | HTT (0.49) | HTTKMT2ASMN1; SMN2TDP1POLB | |
| SCHEMBL8102010 | 0.91 | HTT (0.44) | HTTKMT2ASMN1; SMN2TDP1POLB | |
| SCHEMBL8052197 | 0.91 | HTT (0.44) | HTTKMT2ASMN1; SMN2TDP1POLB | |
| SCHEMBL8102008 | 0.91 | HTT (0.44) | HTTKMT2ASMN1; SMN2TDP1POLB | |
| SCHEMBL10596859 | 0.90 | HTT (0.43) | HTTKMT2ASMN1; SMN2TDP1POLB | |
| SCHEMBL9340969 | 0.89 | HTT (0.42) | HTTKMT2ASMN1; SMN2TDP1POLB | |
| SCHEMBL9340965 | 0.89 | HTT (0.42) | HTTKMT2ASMN1; SMN2TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536442-A | ELECTROOPTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-16 | — | — | US | disclosed |
| US-5324449-A | Substituted phenyl trifluoromethyl ethers | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-06-28 | — | — | US | disclosed |