SCHEMBL906160

SCHEMBL906160

Cc1cc2c(c(C)c1C)Nc1ccccc1S2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 10/20 0.53
MAPT P10636 6/20 0.53
GAA P10253 5/20 0.53
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
ALOX15 P16050 3/20 0.53
TDP1 Q9NUW8 2/20 0.53
BCHE P06276 2/20 0.53
ACHE P22303 2/20 0.53
SNCA P37840 2/20 0.53
CYP1A2 P05177 2/20 0.53
POLB P06746 1/20 0.53
CYP3A4 P08684 1/20 0.53
ADORA3 P0DMS8 1/20 0.53
ALOX12 P18054 1/20 0.53
MAOA P21397 1/20 0.53
CNR1 P21554 1/20 0.53
PTGS1 P23219 1/20 0.53
SLC6A2 P23975 1/20 0.53
HTR2C P28335 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20444659 0.81 NOX1 (0.52) NOX1MAPTGAAMEN1KMT2A
SCHEMBL2586861 0.81 NOX1 (0.55) NOX1MAPTGAAMEN1KMT2A
SCHEMBL28131414 0.79 NOX1 (0.42) NOX1MAPTGAAMEN1KMT2A
SCHEMBL9474465 0.79 NOX1 (0.53) NOX1MAPTGAAMEN1KMT2A
SCHEMBL11427463 0.78 NOX1 (0.45) NOX1MAPTGAAMEN1KMT2A
SCHEMBL194062 0.78 NOX1 (0.61) NOX1MAPTGAAMEN1KMT2A
SCHEMBL31331504 0.78 NOX1 (0.61) NOX1MAPTGAAMEN1KMT2A
SCHEMBL24439558 0.77 NOX1 (0.67) NOX1MAPTGAAMEN1KMT2A
SCHEMBL21214275 0.76 NOX1 (0.60) NOX1MAPTGAAMEN1KMT2A
SCHEMBL11427460 0.75 NOX1 (0.41) NOX1MAPTGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3948414-A1 ELECTRO-OPTIC SUB-ASSEMBLIES AND ASSEMBLIES HAVING AN ELECTROCHROMIC GEL LAYER GENTEX CORPORATION (US) 2022-02-09 EP disclosed
EP-2270116-B1 Color-stabilized electrochromic devices GENTEX CORP (US) 2017-12-20 EP disclosed
EP-2270116-A2 Color-stabilized electrochromic devices Gentex Corporation (US) 2011-01-05 EP disclosed
WO-2003052494-A2 ELECTROCHROMIC DEVICE HAVING A CURRENT-REDUCING ADDITIVE GENTEX CORPORATION (US) 2003-06-26 WO disclosed