SCHEMBL2586861

SCHEMBL2586861

Cc1ccc2c(c1C)Nc1ccccc1S2

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 11/20 0.55
GAA P10253 6/20 0.55
MAPT P10636 6/20 0.55
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
ALOX15 P16050 3/20 0.55
TDP1 Q9NUW8 3/20 0.55
BCHE P06276 2/20 0.55
ACHE P22303 2/20 0.55
SNCA P37840 2/20 0.55
CYP1A2 P05177 1/20 0.55
POLB P06746 1/20 0.55
CYP3A4 P08684 1/20 0.55
ADORA3 P0DMS8 1/20 0.55
ALOX12 P18054 1/20 0.55
MAOA P21397 1/20 0.55
CNR1 P21554 1/20 0.55
PTGS1 P23219 1/20 0.55
SLC6A2 P23975 1/20 0.55
HTR2C P28335 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL194062 0.83 NOX1 (0.61) NOX1GAAMAPTMEN1KMT2A
SCHEMBL31331504 0.83 NOX1 (0.61) NOX1GAAMAPTMEN1KMT2A
SCHEMBL21101750 0.83 NOX1 (0.52) NOX1GAAMAPTMEN1KMT2A
SCHEMBL17746931 0.83 NOX1 (0.52) NOX1GAAMAPTMEN1KMT2A
SCHEMBL16815268 0.83 NOX1 (0.52) NOX1GAAMAPTMEN1KMT2A
SCHEMBL906160 0.81 NOX1 (0.53) NOX1GAAMAPTMEN1KMT2A
SCHEMBL9474044 0.80 NOX1 (0.57) NOX1GAAMAPTMEN1KMT2A
SCHEMBL23018616 0.77 L3MBTL1 (0.54) GAAMAPTALOX15TDP1POLB
SCHEMBL7220609 0.77 GAA (0.41) GAAMAPTADORA3L3MBTL1IDO1
SCHEMBL20537255 0.77 NOX1 (0.44) NOX1GAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11100373-A None JP disclosed
CN-122079798-A Laser molecule with cascade excited state double proton transfer activity, monocrystalline material, and preparation method and application thereof 2026-05-26 CN disclosed
WO-2024260416-A1 ORGANIC COMPOUND, PREPARATION METHOD THEREFOR, AND ELECTRONIC DEVICE TCL科技集团股份有限公司 2024-12-26 WO disclosed
CN-119176817-A Organic compound, preparation method thereof and electronic device TCL科技集团股份有限公司 2024-12-24 CN disclosed
EP-2585073-B1 ANTIVIRAL COMPOUNDS PROSETTA ANTIVIRAL INC (US) 2016-04-27 EP disclosed
US-8809317-B2 Antiviral compounds PROSETTA ANTIVIRAL INC. (US) 2014-08-19 US disclosed
US-8785434-B2 Antiviral compounds PROSETTA ANTIVIRAL INC. (US) 2014-07-22 US disclosed
EP-2585073-A1 ANTIVIRAL COMPOUNDS Prostetta Antiviral Inc. (US) 2013-05-01 EP disclosed
CN-102958525-A Antiviral compounds PROSTETTA ANTIVIRAL INC 2013-03-06 CN disclosed
US-20120302556-A1 Antiviral Compounds PROSETTA ANTIVIRAL INC. (US) 2012-11-29 US disclosed
US-6489336-B2 PHENOTHIAZINE, ACRIDAN, ACRIDONE OXIME, ACRIDONE HYDRAZONE, OR DIBENZODIAZEPINE DERIVATIVES; TYROSINE KINASE INHIBITORS; TREATING ALLERGIC DISEASES EISAI CO., LTD. (JP) 2002-12-03 US disclosed
US-20020103189-A1 Nitrogen-containing tricyclic compounds and drugs containing the same EISAI CO., LTD. 2002-08-01 US disclosed
US-6333322-B1 FOR THERAPY OF ASTHMA, ALLERGIC RHINITIS, ATOPIC DERMATITIS, URTICARIA, HAY FEVER, GASTROINTESTINAL ALLERGY AND FOOD ALLERGY EISAI CO., LTD. (JP) 2001-12-25 US disclosed
JP-H11100373-A NEW PHENOTHIAZINE DERIVATIVE AND ITS MEDICINE EISAI CO LTD 1999-04-13 JP disclosed
EP-0889037-A1 NITROGENOUS TRICYCLIC COMPOUNDS AND DRUGS COMPRISING THE SAME Eisai Co., Ltd. (JP) 1999-01-07 EP disclosed
US-5240762-A Mixed stacked charge transfer complex of donor and acceptor molecules KABUSHIKI KAISHA TOSHIBA (JP) 1993-08-31 US disclosed
EP-0478380-A1 Organic thin film element KABUSHIKI KAISHA TOSHIBA (JP) 1992-04-01 EP disclosed
US-4375006-A ALKYL GALLATE AND PHENOTHIAZINE, ALKYLPHENOTHIAZINE OR 4-TERT-BUTYLCATECHOL ETHYL CORPORATION (US) 1983-02-22 US disclosed
US-4343956-A GALLATE ESTER AND TETRAMETHYL-P-PHENYLENEDIAMINE ETHYL CORPORATION (US) 1982-08-10 US disclosed
US-3945941-A POLYETHYLENE OR POLYPROPYLENE STORAGETANK LINERS OXIRANE CORPORATION (US) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020103189-A1 Nitrogen-containing tricyclic compounds and drugs containing the same HRH2, HRH1, HRH4 NOX1 95/4885GAA 2917/4885MAPT 1551/4885
US-20120302556-A1 Antiviral Compounds HAVCR2, MAVS, EIF2AK2 NOX1 2733/4885GAA 191/4885MAPT 1569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.