Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9803788 | 0.98 | — | — | |
| SCHEMBL8758936 | 0.78 | ALOX5 (0.32) | EPHX1 | |
| SCHEMBL9062930 | 0.76 | — | — | |
| SCHEMBL20869873 | 0.76 | CA1 (0.45) | — | |
| SCHEMBL28907954 | 0.74 | ALOX5 (0.32) | — | |
| SCHEMBL6917339 | 0.74 | — | — | |
| SCHEMBL10608274 | 0.72 | EPHX1 (0.50) | CES2CES1KMT2ANPC1RAB9A | |
| SCHEMBL9062594 | 0.72 | EPHX1 (0.50) | CES2CES1KMT2ANPC1RAB9A | |
| SCHEMBL177813 | 0.72 | EPHX1 (0.50) | CES2CES1KMT2ANPC1RAB9A | |
| SCHEMBL14606390 | 0.72 | EPHX1 (0.50) | CES2CES1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550161-A | COMPOUNDS WHICH CHELATE IRON AND ALUMINUM IONS; TREATMENT OF VARIOUS ANEMIAS, HEMOSIDEROSIS, ALZHEIMER*S DISEASE | ORAL-D (US) | 1996-08-27 | — | — | US | disclosed |
| WO-1992020227-A1 | SUBSTITUTED ORALLY EFFECTIVE ION CHELATORS RELATED TO DEFEROXAMINE | ORAL-D (US) | 1992-11-26 | — | — | WO | disclosed |
| US-5047421-A | Treating trivalent metal overload conditions in humans | ORAL-D (US) | 1991-09-10 | — | — | US | disclosed |
| US-5015664-A | Orally effective ion chelators related to deferoxamine | ORAL D (US) | 1991-05-14 | — | — | US | disclosed |
| US-4684482-A | DEFEROXAMINE DERIVATIVES | ORAL-D (L.P.) (US) | 1987-08-04 | — | — | US | disclosed |
| US-4671901-A | DIFEROXAMINE DERIVATIVES FOR REDUCTION OF METAL ION TUSSUE OV ERLOAD | ORAL-D (US) | 1987-06-09 | — | — | US | disclosed |
| EP-0171414-A1 | ORALLY EFFECTIVE ION CHELATORS RELATED TO DEFEROXAMINE. | ORAL D (US) | 1986-02-19 | — | — | EP | disclosed |
| WO-1985003290-A1 | ORALLY EFFECTIVE ION CHELATORS RELATED TO DEFEROXAMINE | ORAL-D (US) | 1985-08-01 | — | — | WO | disclosed |