Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.48 |
| ▸ | THRA | P10827 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9062630 | 1.00 | PTPN11 (0.48) | PTPN11THRATHRBPLA2G2DS1PR1 | |
| SCHEMBL9062392 | 1.00 | PTPN11 (0.48) | PTPN11THRATHRBPLA2G2DS1PR1 | |
| SCHEMBL9647550 | 0.94 | PTPN11 (0.44) | PTPN11THRATHRBPLA2G2DS1PR1 | |
| SCHEMBL9647578 | 0.94 | PTPN11 (0.44) | PTPN11THRATHRBPLA2G2DS1PR1 | |
| SCHEMBL9396411 | 0.90 | PTPN11 (0.41) | PTPN11THRATHRBPLA2G2DS1PR1 | |
| SCHEMBL9218434 | 0.89 | PTPN11 (0.43) | PTPN11THRATHRBPLA2G2DS1PR1 | |
| SCHEMBL9440286 | 0.89 | PTPN11 (0.43) | PTPN11THRATHRBPLA2G2DS1PR1 | |
| SCHEMBL9224274 | 0.89 | PTPN11 (0.43) | PTPN11THRATHRBPLA2G2DS1PR1 | |
| SCHEMBL9440528 | 0.89 | PTPN11 (0.43) | PTPN11THRATHRBPLA2G2DS1PR1 | |
| SCHEMBL9227237 | 0.88 | RARB (0.44) | PTPN11THRATHRBRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637624-B1 | Antiferroelectric liquid crystal compound | SHOWA SHELL SEKIYU (JP) | 1996-09-25 | — | — | EP | disclosed |
| US-5417885-A | Antiferroelectric liquid crystal compound | SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) | 1995-05-23 | — | — | US | disclosed |
| EP-0637624-A1 | Antiferroelectric liquid crystal compound | Showa Shell Sekiyu Kabushiki Kaisha (JP) | 1995-02-08 | — | — | EP | disclosed |