SCHEMBL9062913

SCHEMBL9062913

C=C[Si](NCCCCCC)(NCCCCCC)NCCCCCC

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.44
ZDHHC2 Q9UIJ5 1/20 0.44
EPHX1 P07099 7/20 0.43
ADH1B P00325 2/20 0.43
ADH1C P00326 2/20 0.43
ADH1A P07327 2/20 0.43
ADH7 P40394 2/20 0.43
ADH4 P08319 1/20 0.43
TSHR P16473 4/20 0.41
ALDH1A1 P00352 2/20 0.40
THRB P10828 1/20 0.36
PPARA Q07869 2/20 0.34
GBA1 P04062 1/20 0.33
CASP2 P42575 1/20 0.33
FAAH O00519 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1277691 0.91 ADH1B (0.37) ZDHHC20ZDHHC2EPHX1ADH1BADH1C
SCHEMBL9816794 0.72 EPHX1 (0.52) EPHX1ADH1BADH1CADH1AADH7
SCHEMBL234029 0.72 EPHX1 (0.52) EPHX1ADH1BADH1CADH1AADH7
SCHEMBL10999448 0.71 ADH1B (0.37) ZDHHC20ZDHHC2EPHX1ADH1BADH1C
SCHEMBL6574513 0.71 TSHR (0.39) ZDHHC20ZDHHC2EPHX1ADH1BADH1C
SCHEMBL10792343 0.70 EPHX1 (0.50) EPHX1ADH1BADH1CADH1AADH7
SCHEMBL1669042 0.70 EPHX1 (0.50) EPHX1ADH1BADH1CADH1AADH7
SCHEMBL9181894 0.70 EPHX1 (0.50) EPHX1ADH1BADH1CADH1AADH7
SCHEMBL28654503 0.70 EPHX1 (0.50) EPHX1ADH1BADH1CADH1AADH7
SCHEMBL10699097 0.70 EPHX1 (0.50) EPHX1ADH1BADH1CADH1AADH7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0510838-B1 Room temperature curable organopolysiloxane composition having mildewproofing property SHINETSU CHEMICAL CO (JP) 1996-08-28 EP disclosed
US-5525660-A RELEASE AGENTS, WATERPROOFING, LUBRICITY SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-06-11 US disclosed
EP-0657517-A1 Organopolysiloxane compositions, their preparation and use, articles coated with them Shin-Etsu Chemical Co., Ltd. (JP) 1995-06-14 EP disclosed
US-5264484-A Room temperature curable organopolysiloxane composition having mildewproofing property SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-11-23 US disclosed
EP-0510838-A1 Room temperature curable organopolysiloxane composition having mildewproofing property SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-10-28 EP disclosed