Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9063188 | 1.00 | MEN1 (0.45) | MEN1KMT2ADNM1SMN1; SMN2ANPEP | |
| SCHEMBL2948432 | 0.81 | MEN1 (0.53) | MEN1KMT2ADNM1ANPEPGAA | |
| SCHEMBL2948436 | 0.81 | MEN1 (0.53) | MEN1KMT2ADNM1ANPEPGAA | |
| SCHEMBL2948433 | 0.81 | MEN1 (0.53) | MEN1KMT2ADNM1ANPEPGAA | |
| Hydrochloric Acid SCHEMBL9063197 | 0.80 | MEN1 (0.52) | MEN1KMT2ADNM1ANPEPGAA | |
| Hydrochloric Acid SCHEMBL9063195 | 0.80 | MEN1 (0.52) | MEN1KMT2ADNM1ANPEPGAA | |
| SCHEMBL8976576 | 0.78 | POLB (0.44) | MEN1KMT2ASMN1; SMN2GAAMAPT | |
| SCHEMBL8751389 | 0.78 | POLB (0.44) | MEN1KMT2ASMN1; SMN2GAAMAPT | |
| SCHEMBL9195269 | 0.76 | GAA (0.49) | MEN1KMT2ADNM1SMN1; SMN2ANPEP | |
| SCHEMBL9190379 | 0.76 | GAA (0.49) | MEN1KMT2ADNM1SMN1; SMN2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545631-A | GAMMA-AMINOBUTYRIC ACID ANTAGONIST; TREATS PETIT-MAL TYPE EPILEPSIES | CIBA-GEIGY CORPORATION (US) | 1996-08-13 | — | — | US | disclosed |
| US-5407922-A | GABA antagonists | CIBA-GEIGY CORPORATION (US) | 1995-04-18 | — | — | US | disclosed |
| US-5229379-A | Gamma-aminobutyric acid antagonists | CIBA-GEIGY CORPORATION (US) | 1993-07-20 | — | — | US | disclosed |