Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 11/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 11/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9063272 | 0.97 | PTGS1 (0.50) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL9063738 | 0.86 | PTGS2 (0.66) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL9063843 | 0.83 | PTGS1 (0.65) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL9063265 | 0.79 | PTGS2 (0.54) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL9063538 | 0.79 | PTGS1 (0.57) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL9063254 | 0.78 | PTGS1 (0.48) | PTGS1PTGS2AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL9063300 | 0.78 | PTGS1 (0.51) | PTGS1PTGS2AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL9140309 | 0.76 | AKR1C3 (0.39) | PTGS1PTGS2AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL9063813 | 0.76 | PTGS2 (0.57) | PTGS1PTGS2OPRK1HTTKMT2A | |
| SCHEMBL9064262 | 0.76 | PTGS1 (0.56) | PTGS1PTGS2OPRK1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641760-B1 | PHENYLALKANOIC ACID DERIVATIVE, PRODUCTION THEREOF, AND SEPARATION OF OPTICAL ISOMERS THEREOF | HISAMITSU PHARMACEUTICAL CO (JP) | 1996-11-06 | — | — | EP | disclosed |
| US-5434292-A | Phenylalkanoic acid derivatives, process for producing the same and process for separating optical isomers thereof | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1995-07-18 | — | — | US | disclosed |
| EP-0641760-A1 | PHENYLALKANOIC ACID DERIVATIVE, PRODUCTION THEREOF, AND SEPARATION OF OPTICAL ISOMERS THEREOF | Hisamitsu Pharmaceutical Co., Inc. (JP) | 1995-03-08 | — | — | EP | disclosed |