Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | BAX | Q07812 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9064070 | 1.00 | LTA4H (0.42) | LTA4HTSHRAOC3KCNA3NR1H2 | |
| SCHEMBL5178753 | 0.80 | LTA4H (0.40) | LTA4HTSHRAOC3KCNA3NR1H2 | |
| SCHEMBL9064188 | 0.78 | AGXT (0.44) | MAOAALDH1A1MAOB | |
| SCHEMBL11541789 | 0.78 | LTA4H (0.45) | LTA4HTSHRAOC3KCNA3NR1H2 | |
| SCHEMBL11541783 | 0.78 | LTA4H (0.45) | LTA4HTSHRAOC3KCNA3NR1H2 | |
| SCHEMBL5513094 | 0.77 | LTA4H (0.43) | LTA4HTSHRAOC3KCNA3CA4 | |
| SCHEMBL1172539 | 0.77 | LTA4H (0.42) | LTA4HTSHRAOC3KCNA3NR1H2 | |
| SCHEMBL10785857 | 0.77 | LTA4H (0.42) | LTA4HTSHRAOC3KCNA3NR1H2 | |
| SCHEMBL11559191 | 0.77 | LTA4H (0.42) | LTA4HTSHRAOC3KCNA3NR1H2 | |
| SCHEMBL4632159 | 0.77 | LTA4H (0.43) | LTA4HTSHRAOC3KCNA3NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733364-A1 | MEDICINAL COMPOSITION FOR CIRCULATORY ORGAN | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-09-25 | — | — | EP | disclosed |