Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 4/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9052687 | 0.90 | HDAC4 (0.38) | HDAC4HRH3ALDH1A1SMN1; SMN2ADRA1D | |
| SCHEMBL480053 | 0.87 | HRH3 (0.45) | HRH3ALDH1A1SMN1; SMN2ADRA1DADRA1A | |
| SCHEMBL9044263 | 0.86 | HDAC4 (0.44) | HDAC4HRH3ALDH1A1SMN1; SMN2ADRA1D | |
| SCHEMBL1407574 | 0.84 | HRH3 (0.52) | HDAC4HRH3ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9041397 | 0.84 | HDAC4 (0.42) | HDAC4HRH3ALDH1A1SMN1; SMN2ADRA1D | |
| SCHEMBL16897482 | 0.81 | ALDH1A1 (0.49) | HRH3ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9041943 | 0.81 | HDAC9 (0.48) | HRH3ALDH1A1SMN1; SMN2ADRA1DADRA1A | |
| SCHEMBL5376177 | 0.78 | HDAC4 (0.62) | HDAC4ADRA1DADRA1AMEN1KMT2A | |
| SCHEMBL9051092 | 0.77 | HDAC4 (0.39) | HDAC4HRH3ALDH1A1SMN1; SMN2ADRA1D | |
| SCHEMBL9435952 | 0.76 | HDAC4 (0.35) | HDAC4HRH3ALDH1A1SMN1; SMN2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994020498-A1 | BENZYLIMIDAZOPYRIDINE DERIVATIVE AS ANGIOTENSIN II RECEPTOR ANTAGONIST | PFIZER INC. (US) | 1994-09-15 | — | — | WO | claimed |
| US-5300668-A | Certain esters of 1-(4-X-methylphenyl)cyclopent-3-ene-1-carboxylic acid, wherein X is a trialkylsilyloxy, bromo or hydroxy group, as intermediates | PFIZER INC. (US) | 1994-04-05 | — | — | US | claimed |
| EP-0690859-A1 | BENZYLIMIDAZOPYRIDINE DERIVATIVES AS ANGIOTENSIN II RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994020499-A1 | BENZYLIMIDAZOPYRIDINE DERIVATIVES AS ANGIOTENSIN II RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1994-09-15 | — | — | WO | disclosed |
| WO-1994020498-A1 | BENZYLIMIDAZOPYRIDINE DERIVATIVE AS ANGIOTENSIN II RECEPTOR ANTAGONIST | PFIZER INC. (US) | 1994-09-15 | — | — | WO | disclosed |
| US-5300668-A | Certain esters of 1-(4-X-methylphenyl)cyclopent-3-ene-1-carboxylic acid, wherein X is a trialkylsilyloxy, bromo or hydroxy group, as intermediates | PFIZER INC. (US) | 1994-04-05 | — | — | US | disclosed |