SCHEMBL9064192

SCHEMBL9064192

CCC(C(=O)O)(C(=O)F)C(=O)F

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
FFAR3 O14843 1/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
THRB P10828 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 2/20 0.32
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL115741 0.82 FFAR3 (0.41) ALDH1A1FFAR3MEN1CYP1A2THRB
SCHEMBL28419811 0.79 FFAR3 (0.39) ALDH1A1FFAR3MEN1CYP1A2THRB
Hydrochloric Acid SCHEMBL28434900 0.79 FFAR3 (0.39) ALDH1A1FFAR3MEN1CYP1A2THRB
Hydrochloric Acid SCHEMBL627728 0.79 FFAR3 (0.39) ALDH1A1FFAR3MEN1CYP1A2THRB
Water SCHEMBL5129171 0.79 FFAR3 (0.39) ALDH1A1FFAR3MEN1CYP1A2THRB
Hydrochloric Acid SCHEMBL3267215 0.79 FFAR3 (0.39) ALDH1A1FFAR3MEN1CYP1A2THRB
SCHEMBL7684976 0.74 ALDH1A1 (0.35) ALDH1A1FFAR3MEN1CYP1A2THRB
SCHEMBL10345101 0.74 ALDH1A1 (0.35) ALDH1A1FFAR3MEN1CYP1A2THRB
Glycolic Acid SCHEMBL18889049 0.72 FFAR3 (0.40) ALDH1A1FFAR3MEN1CYP1A2THRB
SCHEMBL1586402 0.72 ALDH1A1 (0.33) ALDH1A1FFAR3MEN1CYP1A2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0577659-B1 CROSS-LINKING AGENT NYCOMED IMAGING AS (NO) 1996-01-17 EP disclosed
EP-0577659-A1 CROSS-LINKING AGENT. HOLMES MICHAEL JOHN (GB) 1994-01-12 EP disclosed
WO-1992017436-A1 CROSS-LINKING AGENT HOLMES, MICHAEL, JOHN (GB) 1992-10-15 WO disclosed