Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.60 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17785970 | 0.93 | ACE2 (0.50) | ACE2ANPEPERAP2HSD17B10CYP3A4 | |
| SCHEMBL302850 | 0.91 | ACE2 (0.72) | ACE2ANPEPERAP2HSD17B10CYP3A4 | |
| SCHEMBL3522883 | 0.91 | HSD17B10 (0.53) | ACE2ANPEPERAP2HSD17B10CYP3A4 | |
| Trientine SCHEMBL9064137 | 0.89 | ACE2 (0.69) | ACE2ANPEPERAP2HSD17B10CYP3A4 | |
| SCHEMBL2138667 | 0.89 | ACE2 (0.69) | ACE2ANPEPERAP2HSD17B10CYP3A4 | |
| SCHEMBL600834 | 0.89 | ACE2 (0.69) | ACE2ANPEPERAP2HSD17B10CYP3A4 | |
| SCHEMBL6305650 | 0.89 | ACE2 (0.69) | ACE2ANPEPERAP2HSD17B10CYP3A4 | |
| SCHEMBL16078966 | 0.89 | HSD17B10 (0.52) | ACE2ANPEPERAP2HSD17B10CYP3A4 | |
| SCHEMBL26522670 | 0.87 | ACE2 (0.67) | ACE2ANPEPERAP2HSD17B10CYP3A4 | |
| Piperazine SCHEMBL28286909 | 0.87 | ACE2 (0.67) | ACE2ANPEPERAP2HSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996017880-A1 | NOVEL POLYURETHANE TOUGHENER, THERMOSETTING RESIN COMPOSITIONS AND ADHESIVES | THE DEXTER CORPORATION (US) | 1996-06-13 | — | — | WO | disclosed |