Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.63 |
| ▸ | CA1 | P00915 | 3/20 | 0.63 |
| ▸ | CA2 | P00918 | 3/20 | 0.63 |
| ▸ | CA7 | P43166 | 3/20 | 0.63 |
| ▸ | CA9 | Q16790 | 3/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA6 | P23280 | 2/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TPMT | P51580 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30803094 | 0.88 | CA2 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL979735 | 0.88 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8996451 | 0.86 | CA12 (0.74) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2171213 | 0.84 | ERN1 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6953914 | 0.84 | CA12 (0.55) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11906262 | 0.83 | CA12 (0.63) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31022830 | 0.83 | CA12 (0.63) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3660100 | 0.83 | CYP3A4 (0.63) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30356232 | 0.82 | TDP1 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6934301 | 0.82 | CA2 (0.57) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575139-B1 | Fluorogenic reagents for detection of glycoconjugates alpha-ketoacids and diketones | INDIANA UNIVERSITY FOUNDATION (US) | 1996-10-23 | — | — | EP | disclosed |
| US-5310682-A | Fluorogenic reagents for detection of glycoconjugates, α-ketoacids and diketones | INDIANA UNIVERSITY FOUNDATION (US) | 1994-05-10 | — | — | US | disclosed |
| EP-0575139-A1 | Fluorogenic reagents for detection of glycoconjugates alpha-ketoacids and diketones | INDIANA UNIVERSITY FOUNDATION (US) | 1993-12-22 | — | — | EP | disclosed |