Styrene

Styrene

SCHEMBL9064452

C=C(C)C(=O)O.C=C(C)C(=O)O.C=CC(=O)O.C=Cc1ccccc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
TSHR P16473 2/20 0.54
AKR1C3 P42330 1/20 0.47
HTT P42858 1/20 0.43
TDP1 Q9NUW8 2/20 0.42
GLA P06280 1/20 0.42
AKT1 P31749 1/20 0.41
HDAC3 O15379 1/20 0.41
TNKS O95271 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HCAR2 Q8TDS4 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
TNKS2 Q9H2K2 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL3442410 1.00 ALDH1A1 (0.54) ALDH1A1TSHRAKR1C3HTTTDP1
Styrene SCHEMBL8700333 1.00 ALDH1A1 (0.54) ALDH1A1TSHRAKR1C3HTTTDP1
Styrene SCHEMBL9219854 0.98 ALDH1A1 (0.52) ALDH1A1TSHRAKR1C3HTTTDP1
Styrene SCHEMBL9018583 0.96 ALDH1A1 (0.50) ALDH1A1TSHRAKR1C3HTTTDP1
Styrene SCHEMBL22396598 0.96 ALDH1A1 (0.50) ALDH1A1TSHRAKR1C3HTTTDP1
Styrene SCHEMBL10482120 0.96 ALDH1A1 (0.50) ALDH1A1TSHRAKR1C3HTTTDP1
Styrene SCHEMBL6040755 0.94 ALDH1A1 (0.61) ALDH1A1TSHRAKR1C3HTTTDP1
Styrene SCHEMBL76985 0.94 ALDH1A1 (0.61) ALDH1A1TSHRAKR1C3HTTTDP1
Styrene SCHEMBL7753037 0.94 ALDH1A1 (0.61) ALDH1A1TSHRAKR1C3HTTTDP1
Styrene SCHEMBL1680068 0.94 ALDH1A1 (0.61) ALDH1A1TSHRAKR1C3HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5563227-A COMPRISING A HYDROXYALKYL ACRYLATE OR HYDROXYALKYL METHACRYLATE AND METHACRYLIC ACID ALKYL ESTER WITH COPOLYMERIZABLE CROSSLINKING AGENT HAVING TWO OR MORE DOUBLE BONDS MITSUBISHI RAYON COMPANY LTD. (JP) 1996-10-08 US disclosed
US-5560994-A Mat thermoplastic resin composition and laminate therefrom, matting agent therefore, and method for matting thermoplastic resin MITSUBISHI RAYON COMPANY LTD. (JP) 1996-10-01 US disclosed
US-5543463-A BLENDS, COPOLYMER B CONSISTS OF HYDROXYALKYL (METH)ACRYLATE, ALKYL METHACRYLATE, ALKYL ACRYLATE, VINYL AROMATIC AND ANOTHER VINYL MONOMERS AND A CROSSLINKING MONOMER WHICH IS OPTIONAL MITSUBISHI RAYON COMPANY LTD. (JP) 1996-08-06 US disclosed
US-5409989-A Comprising styrene/acrylic/ polyester graft polymers; for xerographic printing MITSUBISHI RAYON CO., LTD. (JP) 1995-04-25 US disclosed