SCHEMBL9064463

SCHEMBL9064463

Cc1cc(C2C(=O)Nc3ccccc32)ccc1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.49
PDE4B Q07343 1/20 0.49
PDE4C Q08493 1/20 0.49
PDE4D Q08499 1/20 0.49
MAPT P10636 5/20 0.47
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
LMNA P02545 1/20 0.47
XBP1 P17861 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
IDO1 P14902 3/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
ALDH1A1 P00352 1/20 0.40
BRD4 O60885 1/20 0.39
KDM4E B2RXH2 3/20 0.38
TDO2 P48775 1/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
JAK2 O60674 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2410715 1.00 PDE4A (0.49) PDE4APDE4BPDE4CPDE4DMAPT
SCHEMBL15619303 0.83 PDE4A (0.49) PDE4APDE4BPDE4CPDE4DMAPT
SCHEMBL18025754 0.79 PDE4A (0.49) PDE4APDE4BPDE4CPDE4DMAPT
SCHEMBL3078111 0.79 JAK2 (0.53) PDE4APDE4BPDE4CPDE4DMAPT
SCHEMBL30564910 0.79 JAK2 (0.53) PDE4APDE4BPDE4CPDE4DMAPT
SCHEMBL18025771 0.78 MAPT (0.49) PDE4APDE4BPDE4CPDE4DMAPT
SCHEMBL18025750 0.77 PDE4A (0.51) PDE4APDE4BPDE4CPDE4DMAPT
SCHEMBL246494 0.77 TLR8 (0.40) MAPTKMT2AMEN1LMNAXBP1
SCHEMBL31728057 0.74 IDO1 (0.51) PDE4APDE4BPDE4CPDE4DMAPT
SCHEMBL2828597 0.74 IDO1 (0.51) PDE4APDE4BPDE4CPDE4DMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4204492-A1 HYDROLYSIS-RESISTANT POLYCARBONATE COMPOSITION Covestro Deutschland AG (DE) 2023-07-05 EP disclosed
WO-2023110961-A1 AT LEAST PARTIALLY BIOBASED LAYERED STRUCTURE WITH GOOD FAVOURABLE PROPERTIES COVESTRO DEUTSCHLAND AG (DE) 2023-06-22 WO disclosed
EP-4197783-A1 AT LEAST PARTIALLY BIOBASED LAYERED STRUCTURE WITH GOOD FLAME RESISTANCE Covestro Deutschland AG (DE) 2023-06-21 EP disclosed
EP-4157940-A1 POYCARBONATE COMPOSITIONS CONTAINING POLYETHERCARBONATE POLYOLS Covestro Deutschland AG (DE) 2023-04-05 EP disclosed
CN-111465804-B Device for dissipating heat from a heat source and use of said device 科思创德国股份有限公司 2023-04-04 CN disclosed
CN-113278261-B High-voltage component 朗盛德国有限责任公司 2023-03-24 CN disclosed
CN-113166529-B Additive manufacturing method using building materials containing metal oxide coated mica 科思创知识产权两合公司 2023-01-10 CN disclosed
CN-111479845-B Method for producing polycarbonate 科思创德国股份有限公司 2022-12-30 CN disclosed
CN-115551946-A Polycarbonate compositions containing polyether carbonate polyols 科思创德国股份有限公司 2022-12-30 CN disclosed
CN-112204103-B Moulded part made of polycarbonate and sterilisable by ionising radiation 科思创知识产权两合公司 2022-12-27 CN disclosed
EP-3368296-A1 MULTI-LAYERED FIBRE COMPOSITE MATERIAL Covestro Deutschland AG (DE) 2018-09-05 EP disclosed
EP-3368297-A1 MULTI-LAYERED FIBRE COMPOSITE MATERIAL Covestro Deutschland AG (DE) 2018-09-05 EP disclosed
EP-3320045-A1 IMPACT-MODIFIED POLYCARBONATE COMPOSITIONS HAVING IMPROVED FLOWABILITY AND A HIGH HEAT DEFLECTION TEMPERATURE Covestro Deutschland AG (DE) 2018-05-16 EP disclosed
CN-101565501-B Phase Boundary Process for the Preparation of Polycarbonates BAYER MATERIALSCIENCE AG 2013-03-06 CN disclosed
CN-1955221-B Moulding compositions based on a thermoplastic polyester with improved flowability LANXESS DEUTSCHLAND GMBH 2010-05-26 CN disclosed
CN-101565501-A Phase Boundary Process for the Preparation of Polycarbonates BAYER MATERIALSCIENCE AG (DE) 2009-10-28 CN disclosed
CN-101519492-A Process for the preparation of polycarbonates and diaryl carbonates BAYER MATERIALSCIENCE AG (DE) 2009-09-02 CN disclosed
CN-1955221-A Moulding compositions based on a thermoplastic polyester with improved flowability LANXESS DEUTSCHLAND GMBH (DE) 2007-05-02 CN disclosed
EP-0733670-A1 Polycarbonate compositions resistant to ionizing radiation Bayer Corporation (US) 1996-09-25 EP disclosed
EP-0376921-A2 Thermoplastic moulding material made of polysiloxane polycarbonate block copolymers BAYER AG (DE) 1990-07-04 EP disclosed