SCHEMBL246494

SCHEMBL246494

Cc1cc(-c2cccc3c2C(c2ccc(O)c(C)c2)C(=O)N3)ccc1O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 1/20 0.40
BRD4 O60885 3/20 0.40
CREBBP Q92793 3/20 0.40
PIM1 P11309 2/20 0.38
HSD17B1 P14061 5/20 0.38
HSD17B2 P37059 5/20 0.38
CDC7 O00311 1/20 0.37
CSNK2A2 P19784 1/20 0.37
CLK1 P49759 1/20 0.37
GSK3B P49841 1/20 0.37
CSNK2B P67870 1/20 0.37
CSNK2A1 P68400 1/20 0.37
CSNK2A3 Q8NEV1 1/20 0.37
ESR2 Q92731 2/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
LMNA P02545 2/20 0.36
MAPT P10636 2/20 0.36
XBP1 P17861 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9580444 0.78 KMT2A (0.46) BRD4CREBBPMEN1KMT2ALMNA
SCHEMBL9064463 0.77 PDE4A (0.49) BRD4GSK3BESR2MEN1KMT2A
SCHEMBL2410715 0.77 PDE4A (0.49) BRD4GSK3BESR2MEN1KMT2A
SCHEMBL5717482 0.74 TLR8 (0.44) TLR8PIM1HSD17B1HSD17B2ESR2
SCHEMBL28482978 0.71 TLR8 (0.48) TLR8PIM1HSD17B1HSD17B2CDC7
SCHEMBL3465804 0.69 HSD17B1 (0.46) TLR8PIM1HSD17B1HSD17B2ESR2
SCHEMBL13678995 0.67 TLR8 (0.70) TLR8HSD17B1HSD17B2ESR2ESR1
SCHEMBL2031812 0.66 TLR8 (0.55) TLR8HSD17B1HSD17B2ESR2MAPT
SCHEMBL28767349 0.66 TLR8 (0.58) TLR8HSD17B1HSD17B2ESR2MAPT
SCHEMBL17725805 0.65 APP (0.61) TLR8PIM1HSD17B1HSD17B2ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3174935-B1 COPOLYCARBONATE COMPOUNDS WITH CYCLIC AND LINEAR OLIGOMERS AND IMPROVED OPTICAL PROPERTIES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-06-21 EP disclosed
EP-3174934-B1 COPOLYCARBONATE COMPOUNDS WITH CYCLIC AND LINEAR OLIGOMERS AND IMPROVED RHEOLOGICAL PROPERTIES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-06-14 EP disclosed
EP-3227374-B1 COPOLYCARBONATE COMPOUNDS WITH IMPROVED RHEOLOGICAL AND OPTICAL PROPERTIES CONTAINING DIGLYCEROLESTER COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-06-01 EP disclosed
US-11114648-B2 UV-protected component for OLEDs COVESTRO DEUTSCHLAND AG (DE) 2021-09-07 US disclosed
CN-107207845-B Copolycarbonate compositions comprising PE-waxes with improved processability 科思创德国股份有限公司 2021-03-12 CN disclosed
EP-3452530-B1 COPOLYCARBONATE AS SUPPORT MATERIAL FOR 3D PRINTING COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2020-09-30 EP disclosed
EP-3097595-B1 UV-PROTECTED COMPONENT FOR OLEDS COVESTRO DEUTSCHLAND AG (DE) 2020-05-27 EP disclosed
EP-3227387-B1 COPOLYCARBONATE COMPOUNDS WITH IMPROVED PROCESSABILITY CONTAINING PE WAXES COVESTRO DEUTSCHLAND AG (DE) 2020-03-11 EP disclosed
EP-3559544-A1 LAYER STRUCTURE WITH SYMBOLS WHICH CAN BE ILLUMINATED, AND USE THEREOF Covestro Deutschland AG (DE) 2019-10-30 EP disclosed
US-10323145-B2 Copolycarbonate compositions with cyclic and linear oligomers and improved optical properties COVESTRO DEUTSCHLAND AG (DE) 2019-06-18 US disclosed
WO-2001019892-A1 CONTAINERS MADE OF A BRANCHED POLYCARBONATE BAYER AKTIENGESELLSCHAFT (DE) 2001-03-22 WO disclosed
WO-2001019894-A1 POLYCARBONATE SLABS BAYER AKTIENGESELLSCHAFT (DE) 2001-03-22 WO disclosed
WO-2001015895-A1 MULTILAYER PLASTIC COMPOSITES AND A METHOD FOR THE PRODUCTION THEREOF BAYER AKTIENGESELLSCHAFT (DE) 2001-03-08 WO disclosed
US-5756641-A Process for producing thermoplastic polycarbonate BAYER AKTIENGESELLSCHAFT (DE) 1998-05-26 US disclosed
EP-0778312-A1 (Co)polycarbonates stabilised against gamma radiation BAYER AG (DE) 1997-06-11 EP disclosed
EP-0411370-A2 Polydiorganosiloxane-polycarbonate block copolycondensates BAYER AG (DE) 1991-02-06 EP disclosed
EP-0374635-A2 Polycarbonate-polysiloxane block copolymers based on dihydroxydiphenyl cycloalkanes BAYER AG (DE) 1990-06-27 EP disclosed
EP-0355642-A2 Use of mixtures of thermoplastic polycarbonates and copolymers of styrene with (meth)-acrylic-acid esters as substrates for optical data recorders BAYER AG (DE) 1990-02-28 EP disclosed
EP-0321831-A2 The use of blends of polycarbonates and styrene polymerizates as substrates for optical memories BAYER AG (DE) 1989-06-28 EP disclosed
EP-0320632-A2 Coated article and process for preparing it BAYER AG (DE) 1989-06-21 EP disclosed