SCHEMBL9064667

SCHEMBL9064667

C=CC(=O)OCCC[Si](C)(C)O

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.61
ALDH1A1 P00352 4/20 0.61
CYP3A4 P08684 2/20 0.61
HPGD P15428 1/20 0.60
TP53 P04637 3/20 0.50
HIF1A Q16665 3/20 0.50
HSD17B10 Q99714 1/20 0.50
THRB P10828 2/20 0.42
ATM Q13315 1/20 0.39
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HCAR2 Q8TDS4 3/20 0.35
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3628945 0.89 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL29467782 0.88 TSHR (0.54) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL308812 0.86 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL26187833 0.86 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL17373005 0.86 TSHR (0.68) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL13138053 0.85 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL1681567 0.85 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL17373014 0.84 TSHR (0.65) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL97671 0.84 TSHR (0.65) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL395892 0.84 TSHR (0.55) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2536786-B1 SURFACE-MODIFIED HYDROGELS AND HYDROGEL MICROPARTICLES DOW CORNING (US) 2015-12-30 EP claimed
US-5391677-A Acrylic-functional organopolysiloxane and method for the preparation thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-02-21 US claimed
EP-3985040-B1 FLUORINE-CONTAINING CURABLE COMPOSITION AND ARTICLE SHINETSU CHEMICAL CO (JP) 2026-03-18 EP disclosed
WO-2025053280-A1 OPTICAL WAVEGUIDE AND OPTICAL MEMBER HAVING OPTICAL WAVEGUIDE 三菱ケミカル株式会社 2025-03-13 WO disclosed
CN-113950495-B Fluorine-containing curable composition and article 信越化学工业株式会社 2025-02-25 CN disclosed
US-11897989-B2 Fluorine-containing curable composition and article SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-02-13 US disclosed
EP-2806293-B1 Wet chemical method for forming an anti-reflective and anti-fogging coating with improved processing capability ZEISS CARL VISION INT GMBH (DE) 2023-06-07 EP disclosed
US-20220220262-A1 FLUORINE-CONTAINING CURABLE COMPOSITION AND ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-07-14 US disclosed
CN-107974178-B Fluorine-containing acrylic compound, method for producing same, curable composition, and article 信越化学工业株式会社 2022-02-25 CN disclosed
US-9669565-B2 Particles and method for producing particles RICOH COMPANY, LTD. (JP) 2017-06-06 US disclosed
US-20150132696-A1 TONER, DEVELOPER, IMAGE FORMING APPARATUS, PARTICLES, METHOD FOR PRODUCING TONER AND METHOD FOR PRODUCING PARTICLES RICOH COMPANY, LTD. (JP) 2015-05-14 US disclosed
US-5391677-A Acrylic-functional organopolysiloxane and method for the preparation thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-02-21 US disclosed
EP-0332400-B1 Photocurable organopolysiloxane composition SHINETSU CHEMICAL CO (JP) 1994-11-30 EP disclosed
US-5357023-A Hydrosilation; dehydrochlorination SHIN-ETSU CHEMICAL CO. (JP) 1994-10-18 US disclosed
EP-0276986-B1 ORGANOPOLYSILOXANES HAVING SILETHYLENE LINKAGES Shin-Etsu Chemical Co., Ltd. (JP) 1993-03-17 EP disclosed
US-5075349-A Surface release agents particularly for use with pressure sensitive adhesive tapes; low peeling resistance SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-12-24 US disclosed
US-4943613-A Photocurable organopolysiloxane composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1990-07-24 US disclosed
US-4910232-A Ultraviolet-curable organopolysiloxane composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1990-03-20 US disclosed
EP-0332400-A2 Photocurable organopolysiloxane composition Shin-Etsu Chemical Co., Ltd. (JP) 1989-09-13 EP disclosed
EP-0276986-A2 Organopolysiloxanes having silethylene linkages Shin-Etsu Chemical Co., Ltd. (JP) 1988-08-03 EP disclosed