SCHEMBL3628945

SCHEMBL3628945

C=CC(=O)OCCC[Si](C)(O)O

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.61
ALDH1A1 P00352 4/20 0.61
CYP3A4 P08684 2/20 0.61
HPGD P15428 1/20 0.60
TP53 P04637 3/20 0.50
HIF1A Q16665 3/20 0.50
HSD17B10 Q99714 1/20 0.50
THRB P10828 2/20 0.42
ATM Q13315 1/20 0.39
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HCAR2 Q8TDS4 3/20 0.35
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9064667 0.89 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL308812 0.86 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL26187833 0.86 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL17373005 0.86 TSHR (0.68) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL13138053 0.85 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL1681567 0.85 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL17373014 0.84 TSHR (0.65) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL97671 0.84 TSHR (0.65) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL395892 0.84 TSHR (0.55) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL20573003 0.84 TSHR (0.55) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115820119-A Resin composition, coating agent, and article DIC株式会社 2023-03-21 CN disclosed
CN-112368338-B Aqueous resin composition, coating agent, and article DIC株式会社 2022-06-14 CN disclosed
US-10774062-B2 Photocuring method, compound and composition used therein FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2020-09-15 US disclosed
EP-3409709-B1 PHOTOCURING METHOD, COMPOUND AND COMPOSITION USED THEREIN FUJIFILM WAKO PURE CHEMICAL CORP (JP) 2020-08-19 EP disclosed
US-20190055210-A1 PHOTOCURING METHOD, COMPOUND AND COMPOSITION USED THEREIN FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2019-02-21 US disclosed
EP-3409709-A1 PHOTOCURING METHOD, COMPOUND AND COMPOSITION USED THEREIN FUJIFILM Wako Pure Chemical Corporation (JP) 2018-12-05 EP disclosed
EP-2005236-B1 SPD LIGHT VALVES INCORPORATING FILMS COMPRISING IMPROVED MATRIX POLYMERS AND METHODS FOR MAKING SUCH MATRIX POLYMERS RESEARCH FRONTIERS INC (US) 2018-02-07 EP disclosed
US-8299185-B2 Curable cage-type silicone copolymer and process for production thereof and curable resin composition comprising curable cage-type silicone copolymer and cured product thereof NIPPON STEEL CHEMICAL CO., LTD. (JP) 2012-10-30 US disclosed
US-20100280190-A1 CURABLE CAGE-TYPE SILICONE COPOLYMER AND PROCESS FOR PRODUCTION THEREOF AND CURABLE RESIN COMPOSITION COMPRISING CURABLE CAGE-TYPE SILICONE COPOLYMER AND CURED PRODUCT THEREOF NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2010-11-04 US disclosed
US-7791788-B2 SPD light valves incorporating films comprising improved matrix polymers and methods for making such matrix polymers RESEARCH FRONTIERS INCORPORATED (US) 2010-09-07 US disclosed
EP-2005236-A2 SPD LIGHT VALVES INCORPORATING FILMS COMPRISING IMPROVED MATRIX POLYMERS AND METHODS FOR MAKING SUCH MATRIX POLYMERS RESEARCH FRONTIERS INCORPORATED (US) 2008-12-24 EP disclosed
WO-2007097796-A2 SPD LIGHT VALVES INCORPORATING FILMS COMPRISING IMPROVED MATRIX POLYMERS AND METHODS FOR MAKING SUCH MATRIX POLYMERS RESEARCH FRONTIERS INCORPORATED (US) 2007-08-30 WO disclosed
US-20070195401-A1 SPD LIGHT VALVES INCORPORATING FILMS COMPRISING IMPROVED MATRIX POLYMERS AND METHODS FOR MAKING SUCH MATRIX POLYMERS RESEARCH FRONTIERS INCORPORATED 2007-08-23 US disclosed
US-6548614-B2 Film-forming organosilicate compounds DAIKIN INDUSTRIES, LTD. (JP) 2003-04-15 US disclosed
US-20010031850-A1 Stain-proofing agent for preventing adherence of stain and non-aqueous composition for paints containing said agent DAIKIN INDUSTRIES, LTD. (JP) 2001-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190055210-A1 PHOTOCURING METHOD, COMPOUND AND COMPOSITION USED THEREIN ESD, TMT1A, PAM TSHR 4741/4885ALDH1A1 23/4885CYP3A4 2435/4885
US-10774062-B2 Photocuring method, compound and composition used therein ESD, TMT1A, PAM TSHR 4741/4885ALDH1A1 23/4885CYP3A4 2435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.