2-Aminopyridine

2-Aminopyridine

SCHEMBL9064720

Nc1ccccn1.Nc1ccccn1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 1.00
NOS1 P29475 1/20 1.00
NOS2 P35228 1/20 1.00
PI4KA P42356 1/20 1.00
PI4K2B Q8TCG2 1/20 1.00
PI4K2A Q9BTU6 1/20 1.00
PI4KB Q9UBF8 1/20 1.00
KDM4E B2RXH2 6/20 0.50
LMNA P02545 3/20 0.50
CCR1 P32246 2/20 0.50
CCR5 P51681 2/20 0.50
CCR8 P51685 2/20 0.50
CYP1A2 P05177 1/20 0.50
POLB P06746 1/20 0.50
METAP1 P53582 1/20 0.50
BLM P54132 1/20 0.50
HIF1A Q16665 1/20 0.50
DOHH Q9BU89 1/20 0.50
P4HTM Q9NXG6 1/20 0.50
HSP90AA1 P07900 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Aminopyridine SCHEMBL29392931 1.00
2-Aminopyridine SCHEMBL2775240 1.00
2-Aminopyridine SCHEMBL17844 1.00
2-Aminopyridine SCHEMBL2333406 0.97
2-Aminopyridine SCHEMBL20496124 0.97
2-Aminopyridine SCHEMBL70318 0.97
2-Aminopyridine SCHEMBL4938381 0.97
2-Aminopyridine SCHEMBL8135890 0.97 NOS3 (0.94) NOS3NOS1NOS2PI4KAPI4K2B
2-Aminopyridine SCHEMBL15012466 0.97
2-Aminopyridine SCHEMBL2692432 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118306985-A Preparation method and application of nitrogen-doped graphene aerogel material 内蒙古工业大学 2024-07-09 CN disclosed
CN-103228692-B Coupled Glass Fiber Reinforced Polyoxymethylene 塞拉尼斯销售德国有限公司 2017-05-31 CN disclosed
CN-106661024-A Organic light-emitting compound and organic electroluminescent element using same 株式会社斗山 2017-05-10 CN disclosed
EP-0708795-A4 HEAT-RESISTANT POLYIMIDE BLENDS AND LAMINATES UNIV AKRON (US) 1996-08-07 EP disclosed
EP-0708795-A1 HEAT-RESISTANT POLYIMIDE BLENDS AND LAMINATES The University of Akron (US) 1996-05-01 EP disclosed
WO-1995002627-A1 HEAT-RESISTANT POLYIMIDE BLENDS AND LAMINATES THE UNIVERSITY OF AKRON (US) 1995-01-26 WO disclosed