Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16227796 | 0.84 | KDM4E (0.59) | KDM4EKMT2AMGAMTDP1MAPT | |
| SCHEMBL1975267 | 0.82 | KDM4E (0.45) | KDM4EKMT2AMGAMTDP1MAPT | |
| SCHEMBL10875426 | 0.80 | KDM4E (0.46) | KDM4EKMT2AMGAMTDP1MAPT | |
| SCHEMBL9907330 | 0.78 | KDM4E (0.53) | KDM4EKMT2AMGAMTDP1ALOX15 | |
| SCHEMBL4751890 | 0.78 | KDM4E (0.66) | KDM4EKMT2AMGAMTDP1ALOX15 | |
| SCHEMBL31385428 | 0.78 | KDM4E (0.66) | KDM4EKMT2AMGAMTDP1ALOX15 | |
| SCHEMBL1088781 | 0.75 | KDM4E (0.67) | KDM4EKMT2AMGAMTDP1MAPT | |
| SCHEMBL2907723 | 0.75 | IGFBP3 (0.43) | KDM4EKMT2ATDP1MAPTRAB9A | |
| SCHEMBL7174003 | 0.75 | MGAM (0.44) | KDM4EMGAMTDP1MAPTRAB9A | |
| SCHEMBL16227887 | 0.74 | KDM4E (0.56) | KDM4EKMT2AMGAMTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8040990-A | — | — | None | — | — | JP | disclosed |
| US-5565612-A | Substituted 2-chloro-3,4,5-trifluorobenzenes and a process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-10-15 | — | — | US | disclosed |
| JP-H0840990-A | SUBSTITUTED 2-CHLORO-3,4,5-TRIFLUOROBENZENE AND ITS PRODUCTION | HOECHST AG | 1996-02-13 | — | — | JP | disclosed |