Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9064819 | 0.91 | TDP1 (0.38) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL366726 | 0.90 | — | — | |
| SCHEMBL35945 | 0.90 | — | — | |
| SCHEMBL367625 | 0.90 | — | — | |
| SCHEMBL6451815 | 0.88 | TDP1 (0.46) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| Ammonia Solution, Strong SCHEMBL1025751 | 0.88 | TDP1 (0.46) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL28153453 | 0.88 | TDP1 (0.46) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| Lactic Acid SCHEMBL27586439 | 0.84 | TP53 (0.46) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| Alcohol SCHEMBL6194629 | 0.84 | TDP1 (0.43) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL28152341 | 0.82 | TDP1 (0.42) | TDP1TSHRCYP3A4MAPTCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563274-A | Process of preparing optically active alpha-chlorocarboxylic esters | RHONE-POULENC CHIMIE (FR) | 1996-10-08 | — | — | US | disclosed |
| US-5049676-A | Chemical intermediates for herbicides | RHONE-POULENC CHIMIE (FR) | 1991-09-17 | — | — | US | disclosed |