Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL1025751

C=CCOC(=O)C(C)O.N

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.46
TSHR P16473 3/20 0.41
CYP3A4 P08684 3/20 0.39
MAPT P10636 3/20 0.37
CACNA1B Q00975 1/20 0.37
APBA1 Q02410 1/20 0.37
ALDH1A1 P00352 3/20 0.34
HSD17B10 Q99714 2/20 0.34
CYP2C9 P11712 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
TP53 P04637 2/20 0.32
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32
USP2 O75604 1/20 0.32
LMNA P02545 1/20 0.32
RECQL P46063 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35945 0.98
SCHEMBL367625 0.98
SCHEMBL366726 0.98
SCHEMBL28153453 0.95 TDP1 (0.46) TDP1TSHRCYP3A4MAPTCACNA1B
SCHEMBL6451815 0.95 TDP1 (0.46) TDP1TSHRCYP3A4MAPTCACNA1B
Alcohol SCHEMBL6194629 0.91 TDP1 (0.43) TDP1TSHRCYP3A4MAPTCACNA1B
Lactic Acid SCHEMBL27586439 0.91 TP53 (0.46) TDP1TSHRCYP3A4MAPTCACNA1B
SCHEMBL28152341 0.90 TDP1 (0.42) TDP1TSHRCYP3A4MAPTCACNA1B
SCHEMBL9064822 0.88 TDP1 (0.41) TDP1TSHRCYP3A4MAPTCACNA1B
SCHEMBL28102887 0.88 TDP1 (0.41) TDP1TSHRCYP3A4MAPTCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160015731-A1 A TOPICAL ANTIVIRAL COMPOSITION CONTAINING A LOCAL ANESTHETIC AND METHOD OF MAKING THE SAME NAL PHARMACEUTICALS, LTD. (CN) 2016-01-21 US claimed
WO-2014159731-A1 A TOPICAL ANTIVIRAL COMPOSITION CONTAINING A LOCAL ANESTHETIC AND METHOD OF MAKING THE SAME NAL PHARMACEUTICALS, LTD (CN) 2014-10-02 WO claimed
US-20140171490-A1 Method and Device for Ophthalmic Administration of Active Pharmaceutical Ingredients PHARMALINGT INC. (US) 2014-06-19 US claimed
EP-1848541-A2 METHOD AND DEVICE FOR OPHTHALMIC ADMINISTRATION OF ACTIVE PHARMACEUTICAL INGREDIENTS Pharmalight Inc. (US) 2007-10-31 EP claimed
WO-2006124899-A2 PRODUCTION OF DERIVATIVES OF LACTIDE, PRODUCTION OF LACTIDES, AND USE OF LACTIDE IN FOODS AND TO PRODUCE POLYMERS CARGILL, INCORPORATED (US) 2006-11-23 WO claimed
WO-2006124633-A1 PRODUCTION OF LACTIC ACID CARGILL, INCORPORATED (US) 2006-11-23 WO claimed
WO-2006082588-A2 METHOD AND DEVICE FOR OPHTHALMIC ADMINISTRATION OF ACTIVE PHARMACEUTICAL INGREDIENTS PHARMALIGHT INC. (US) 2006-08-10 WO claimed
US-20050069499-A1 Foamable compositions, processes of preparing same and uses thereof PERRIGO ISRAEL PHARMACEUTICALS LTD. (IL) 2005-03-31 US claimed
US-12036310-B2 Skin rejuvenating composition Endoderm Laboratories, LLC (US) 2024-07-16 US disclosed
EP-4308135-A1 THERAPEUTIC USE OF ENGINEERED POSTBIOTICS COMPRISING BACTERIOCINS AND/OR ENDOLYSINS Eligo Bioscience (FR) 2024-01-24 EP disclosed
US-11839645-B2 Therapeutic use of engineered postbiotics comprising bacteriocins and/or endolysins ELIGO BIOSCIENCE (FR) 2023-12-12 US disclosed
US-20230331711-A1 CRYSTALLINE PHARMACEUTICAL AND METHODS OF PREPARATION AND USE THEREOF BAUSCH + LOMB IRELAND LIMITED (IE) 2023-10-19 US disclosed
WO-2023137098-A1 COMPOSITIONS AND METHODS FOR IMPROVING SEXUAL SENSORY DISORDERS WINSANTOR, INC. (US) 2023-07-20 WO disclosed
US-20230218505-A1 COSMETIC USE OF ENGINEERED POSTBIOTICS COMPRISING BACTERIOCINS AND/OR ENDOLYSINS ELIGO BIOSCIENCE (FR) 2023-07-13 US disclosed
US-5750732-A SOLVENT EXTRACTION; DEHYDRATION CHRONOPOL, INC. (US) 1998-05-12 US disclosed
CN-1136309-A Method to produce cyclic esters BIOPAK TECHNOLOGY LTD (US) 1996-11-20 CN disclosed
EP-0722433-A4 1996-07-31 EP disclosed
EP-0722433-A1 METHOD TO PRODUCE CYCLIC ESTERS BioPak Technology, Ltd. (US) 1996-07-24 EP disclosed
US-5420304-A Esterification and cyclization then solvent extraction BIOPAK TECHNOLOGY, LTD. (US) 1995-05-30 US disclosed
WO-1995009142-A1 METHOD TO PRODUCE CYCLIC ESTERS BIOPAK TECHNOLOGY, LTD. (US) 1995-04-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331711-A1 CRYSTALLINE PHARMACEUTICAL AND METHODS OF PREPARATION AND USE THEREOF VCAM1, ICAM1, HLA-DRB1 TDP1 1007/4885TSHR 3522/4885CYP3A4 347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.