Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 13/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.74 |
| ▸ | PGR | P06401 | 5/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.74 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.74 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.74 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.74 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.74 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.74 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.74 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.74 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.74 |
| ▸ | DRD2 | P14416 | 4/20 | 0.74 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.74 |
| ▸ | LMNA | P02545 | 4/20 | 0.74 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoconazole SCHEMBL24534353 | 0.85 | IDO1 (1.00) | IDO1CYP2C9PGRADORA3SLC6A2 | |
| Isoconazole SCHEMBL148289 | 0.85 | IDO1 (1.00) | IDO1CYP2C9PGRADORA3SLC6A2 | |
| Isoconazole SCHEMBL29692926 | 0.85 | IDO1 (1.00) | IDO1CYP2C9PGRADORA3SLC6A2 | |
| Isoconazole SCHEMBL148288 | 0.85 | IDO1 (1.00) | IDO1CYP2C9PGRADORA3SLC6A2 | |
| Isoconazole SCHEMBL21179422 | 0.84 | IDO1 (0.98) | IDO1CYP2C9PGRADORA3SLC6A2 | |
| Tioconazole SCHEMBL3682100 | 0.83 | PGR (1.00) | IDO1CYP2C9PGRADORA3SLC6A2 | |
| Tioconazole SCHEMBL29881791 | 0.83 | PGR (1.00) | IDO1CYP2C9PGRADORA3SLC6A2 | |
| Tioconazole SCHEMBL29882046 | 0.83 | PGR (1.00) | IDO1CYP2C9PGRADORA3SLC6A2 | |
| Tioconazole SCHEMBL41355 | 0.83 | PGR (1.00) | IDO1CYP2C9PGRADORA3SLC6A2 | |
| Tioconazole SCHEMBL3682098 | 0.83 | PGR (1.00) | IDO1CYP2C9PGRADORA3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5505949-A | MIXTURE OF CLORTRIMAZOLE, BETAMETHASONE AND SALICYLIC ACID | BENITEZ JUAN E (US) | 1996-04-09 | — | — | US | disclosed |
| US-4446145-A | BENZOYL PEROXIDE, CHLOROPHENYLIMIDAZOLE | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-05-01 | — | — | US | disclosed |