Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 0.43 |
| ▸ | CTSD | P07339 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9064939 | 1.00 | REN (0.43) | RENCTSDBACE1MMP2MMP9 | |
| SCHEMBL7273054 | 0.86 | REN (0.46) | RENBACE1MMP2MMP9MMP8 | |
| SCHEMBL7276322 | 0.86 | REN (0.46) | RENBACE1MMP2MMP9MMP8 | |
| SCHEMBL7286960 | 0.75 | REN (0.54) | REN | |
| SCHEMBL7280678 | 0.74 | REN (0.53) | REN | |
| SCHEMBL7267118 | 0.72 | REN (0.46) | RENCTSDBACE1 | |
| SCHEMBL7290537 | 0.69 | REN (0.52) | REN | |
| SCHEMBL7292837 | 0.68 | BACE1 (0.49) | RENBACE1 | |
| Hydrochloric Acid SCHEMBL7286804 | 0.67 | BACE1 (0.48) | RENBACE1 | |
| SCHEMBL7294736 | 0.66 | BACE1 (0.48) | RENCTSDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5481036-A | RENIN INHIBITORS, HYPOTENSIVE AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |