Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | ALPI | P09923 | 1/20 | 0.31 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15255475 | 1.00 | HTT (0.40) | HTTALDH1A1PARP1EPHX1CYP2C9 | |
| SCHEMBL9064999 | 0.80 | EPHX1 (0.34) | ALDH1A1EPHX1CYP2C9SMN1; SMN2CYP1A2 | |
| SCHEMBL9065002 | 0.80 | EPHX1 (0.34) | ALDH1A1EPHX1CYP2C9SMN1; SMN2CYP1A2 | |
| SCHEMBL6749586 | 0.78 | EPHX1 (0.39) | ALDH1A1EPHX1CYP2C9SMN1; SMN2CYP1A2 | |
| SCHEMBL6749593 | 0.78 | EPHX1 (0.39) | ALDH1A1EPHX1CYP2C9SMN1; SMN2CYP1A2 | |
| SCHEMBL2429606 | 0.76 | EPHX1 (0.38) | EPHX1MEN1KMT2AKDM4EALOX15 | |
| SCHEMBL15255473 | 0.73 | HTT (0.43) | HTTALDH1A1PARP1CYP1A2CYP2C19 | |
| SCHEMBL5176644 | 0.73 | HTT (0.43) | HTTALDH1A1PARP1CYP1A2CYP2C19 | |
| SCHEMBL12120877 | 0.73 | HTT (0.43) | HTTALDH1A1PARP1CYP1A2CYP2C19 | |
| SCHEMBL24637748 | 0.73 | EPHX1 (0.35) | EPHX1CYP2C9SMN1; SMN2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523360-A | IMPROVES MELT-FLOW PROPERTIES | AKZO NOBEL N. V. (NL) | 1996-06-04 | — | — | US | disclosed |
| EP-0648240-A1 | PROCESS FOR THE MODIFICATION OF POLYPHENYLENE ETHER RESIN COMPOSITIONS | Akzo Nobel N.V. (NL) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994001485-A1 | PROCESS FOR THE MODIFICATION OF POLYPHENYLENE ETHER RESIN COMPOSITIONS | AKZO NOBEL N.V. (NL) | 1994-01-20 | — | — | WO | disclosed |