Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6749586 | 1.00 | EPHX1 (0.39) | EPHX1MEN1KMT2ACYP2C9CYP1A2 | |
| SCHEMBL6240862 | 0.79 | NFKB1 (0.30) | — | |
| SCHEMBL24637748 | 0.78 | EPHX1 (0.35) | EPHX1MEN1KMT2ACYP2C9CYP1A2 | |
| SCHEMBL9065004 | 0.78 | HTT (0.40) | EPHX1MEN1KMT2ACYP2C9CYP1A2 | |
| SCHEMBL15255475 | 0.78 | HTT (0.40) | EPHX1MEN1KMT2ACYP2C9CYP1A2 | |
| SCHEMBL9064999 | 0.77 | EPHX1 (0.34) | EPHX1MEN1KMT2ACYP2C9CYP1A2 | |
| SCHEMBL9065002 | 0.77 | EPHX1 (0.34) | EPHX1MEN1KMT2ACYP2C9CYP1A2 | |
| SCHEMBL16188979 | 0.77 | POLB (0.33) | RAB9APOLBNPC1 | |
| SCHEMBL23682612 | 0.77 | EPHX1 (0.34) | EPHX1MEN1KMT2ACYP2C9CYP1A2 | |
| SCHEMBL6859267 | 0.76 | KDM4E (0.46) | EPHX1MEN1KMT2ACYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1092729-B1 | POLYMERIZATION CATALYST, NOVEL TRANSITION METAL COMPOUND, AND POLYMERIZATION METHOD AND COPOLYMER USING THEM | MITSUI CHEMICALS INC (JP) | 2012-09-26 | — | — | EP | disclosed |
| US-6703459-B1 | ORGANIC TRANSITION METAL COMPLEXES HAVING SPECIFIC STRUCTURE, WHICH CAN FORM COPOLYMERS HAVING LINKAGE FORMED BY MIGRATION OF ACTIVE HYDROGEN OF UNSATURATED MONOMER | MITSUI CHEMICALS, INC. (JP) | 2004-03-09 | — | — | US | disclosed |
| EP-1092729-A1 | POLYMERIZATION CATALYST, NOVEL TRANSITION METAL COMPOUND, AND POLYMERIZATION METHOD AND COPOLYMER USING THEM | Mitsui Chemicals, Inc. (JP) | 2001-04-18 | — | — | EP | disclosed |