Propionic Acid

Propionic Acid

SCHEMBL9065041

CCC(=O)O.NC(N)(C(=O)O)C(O)O

nearest known ligand 0.48

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.48
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP1A2 P05177 1/20 0.39
THRB P10828 1/20 0.39
KMT2A Q03164 1/20 0.39
CYP2D6 P10635 1/20 0.32
TSHR P16473 1/20 0.32
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
CPT2 P23786 1/20 0.31
ACLY P53396 1/20 0.31
GABRR1 P24046 2/20 0.31
LMNA P02545 1/20 0.31
SLC22A6 Q4U2R8 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
GRM2 Q14416 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tert-Butylamine SCHEMBL3414252 0.73 FFAR3 (0.67) FFAR3MEN1ALDH1A1CYP1A2THRB
SCHEMBL7532147 0.73 TSHR (0.42) FFAR3MEN1ALDH1A1CYP1A2THRB
Propionic Acid SCHEMBL7138574 0.73
Propionic Acid SCHEMBL28660894 0.71 FFAR3 (0.62) FFAR3MEN1ALDH1A1CYP1A2THRB
Propionic Acid SCHEMBL1836514 0.71
Propionic Acid SCHEMBL5573589 0.70 FFAR3 (0.53) FFAR3MEN1ALDH1A1CYP1A2THRB
Glycerin SCHEMBL1685705 0.70 FFAR3 (0.53) FFAR3MEN1ALDH1A1KMT2ALMNA
Glycerin SCHEMBL22720645 0.70 FFAR3 (0.53) FFAR3MEN1ALDH1A1KMT2ALMNA
Propionic Acid SCHEMBL27791535 0.70
Propionic Acid SCHEMBL27342318 0.70 FFAR3 (0.71) FFAR3MEN1ALDH1A1KMT2ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0707595-A1 PEPTIDASE RESISTANT THROMBIN RECEPTOR PEPTIDE LIGAND THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1996-04-24 EP disclosed
WO-1995001372-A1 PEPTIDASE RESISTANT THROMBIN RECEPTOR PEPTIDE LIGAND THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1995-01-12 WO disclosed