Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CASR | P41180 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL114856 | 0.84 | TDP1 (0.44) | TDP1TP53CASRCYP1A2CYP2A6 | |
| SCHEMBL9346593 | 0.84 | TDP1 (0.44) | TDP1TP53CASRCYP1A2CYP2A6 | |
| SCHEMBL6546944 | 0.83 | MAPT (0.47) | TDP1TP53CASRCYP2A6ALDH1A1 | |
| SCHEMBL18242406 | 0.82 | TDP1 (0.42) | TDP1TP53CASRCYP1A2CYP2A6 | |
| SCHEMBL17972841 | 0.80 | CASR (0.41) | TDP1TP53CASRCYP1A2CYP2A6 | |
| SCHEMBL12180439 | 0.80 | TDP1 (0.46) | TDP1TP53CASRCYP1A2CYP2A6 | |
| SCHEMBL18546040 | 0.80 | CASR (0.53) | TDP1TP53CASRCYP1A2CYP2A6 | |
| SCHEMBL22667817 | 0.80 | TDP1 (0.41) | TDP1TP53CASRCYP1A2CYP2A6 | |
| SCHEMBL3655726 | 0.80 | TDP1 (0.41) | TDP1TP53CASRCYP1A2CYP2A6 | |
| SCHEMBL7610097 | 0.80 | TDP1 (0.46) | TDP1TP53CASRCYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210353-A | Transarylalkylation | AMOCO CORPORATION (US) | 1993-05-11 | — | — | US | claimed |
| EP-3133444-A1 | CHEMICALLY AMPLIFIED RESIST MATERIAL, PATTERN-FORMING METHOD, COMPOUND, AND PRODUCTION METHOD OF COMPOUND | OSAKA UNIVERSITY (JP) | 2017-02-22 | — | — | EP | disclosed |
| EP-0564979-B1 | Method for the production of dixylylpropane | HOECHST AG (DE) | 1996-08-28 | — | — | EP | disclosed |
| EP-0499925-B1 | Process for the preparation of 2,2-Bis-(3,4-Dimethyl-Phenyl)-propane | BAYER AG (DE) | 1995-10-18 | — | — | EP | disclosed |
| US-5300717-A | Reacting o-xylene with propene; Friedel-Crafts catalyst; dehydrogenation. chlorination, condensation; intermediate for bisanhydride precursor for polyimides | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-05 | — | — | US | disclosed |
| EP-0564979-A2 | Method for the production of dixylylpropane | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-10-13 | — | — | EP | disclosed |
| US-5210353-A | Transarylalkylation | AMOCO CORPORATION (US) | 1993-05-11 | — | — | US | disclosed |
| EP-0499925-A1 | Process for the preparation of 2,2-Bis-(3,4-Dimethyl-Phenyl)-propane | BAYER AG (DE) | 1992-08-26 | — | — | EP | disclosed |