SCHEMBL6546944

SCHEMBL6546944

Cc1ccc(C(C)(C)c2ccccc2)c(C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.47
MEN1 O00255 1/20 0.47
LMNA P02545 1/20 0.47
KMT2A Q03164 1/20 0.47
GPR55 Q9Y2T6 1/20 0.47
CNR1 P21554 3/20 0.42
CNR2 P34972 3/20 0.42
CASR P41180 3/20 0.41
ESR1 P03372 3/20 0.41
ESR2 Q92731 3/20 0.41
ALDH1A1 P00352 2/20 0.41
CYP3A4 P08684 2/20 0.41
KIF11 P52732 2/20 0.40
POLB P06746 1/20 0.37
HPGD P15428 1/20 0.37
ALOX12 P18054 1/20 0.37
GFER P55789 1/20 0.37
TDP1 Q9NUW8 2/20 0.35
TP53 P04637 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9242984 0.85 HTT (0.41) MAPTMEN1LMNAKMT2AGPR55
SCHEMBL7178497 0.84 ESR1 (0.47) MAPTMEN1LMNAKMT2AGPR55
SCHEMBL16191085 0.84 CNR1 (0.42) MAPTMEN1LMNAKMT2AGPR55
SCHEMBL9065284 0.83 TDP1 (0.44) MAPTMEN1LMNAKMT2AGPR55
SCHEMBL9757648 0.81 ESR2 (0.57) MAPTMEN1LMNAKMT2AGPR55
SCHEMBL10608720 0.81 CNR1 (0.41) MAPTMEN1LMNAKMT2AGPR55
SCHEMBL11022050 0.81 KIF11 (0.44) MAPTMEN1LMNAKMT2AGPR55
SCHEMBL11621119 0.80 LMNA (0.47) MAPTMEN1LMNAKMT2AGPR55
SCHEMBL9421204 0.79 ESR1 (0.46) MAPTMEN1KMT2ACNR1CNR2
SCHEMBL7763649 0.78 MEN1 (0.52) MAPTMEN1LMNAKMT2AGPR55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5210353-A Transarylalkylation AMOCO CORPORATION (US) 1993-05-11 US claimed
US-20150004484-A1 ORGANIC ELECTROLYTE AND ORGANIC ELECTROLYTE STORAGE BATTERY JX NIPPON OIL & ENERGY CORPORATION (JP) 2015-01-01 US disclosed
US-20140370375-A1 ORGANIC ELECTROLYTE AND ORGANIC ELECTROLYTE STORAGE BATTERY JX NIPPON OIL & ENERGY CORPORATION (JP) 2014-12-18 US disclosed
EP-2797154-A1 ORGANIC ELECTROLYTE, AND ORGANIC ELECTROLYTE STORAGE BATTERY JX Nippon Oil & Energy Corporation (JP) 2014-10-29 EP disclosed
EP-2797153-A1 ORGANIC ELECTROLYTE, AND ORGANIC ELECTROLYTE STORAGE BATTERY JX Nippon Oil & Energy Corporation (JP) 2014-10-29 EP disclosed
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0259798-B1 Electrical insulating oil composition NIPPON PETROCHEMICALS CO LTD (JP) 1997-12-10 EP disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed
EP-0399284-B1 Method for the production of geminal diarylalkanes, geminal diarylalkanes and alk(en)ylated aromatic compounds BAYER AG (DE) 1995-08-02 EP disclosed
US-5210353-A Transarylalkylation AMOCO CORPORATION (US) 1993-05-11 US disclosed
US-5136114-A PROCESS FOR THE PREPARATION OF GEMINAL DIARYLALKANES, NEW GEMINAL DIARYLALKANES AND ALK(EN)YLATED AROMATIC COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1992-08-04 US disclosed
US-5081758-A Impregnation with aromatic hydrocarbon mixture NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1992-01-21 US disclosed
US-5017733-A Aromatic hydrocarbons NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1991-05-21 US disclosed
EP-0399284-A2 Method for the production of geminal diarylalkanes, geminal diarylalkanes and alk(en)ylated aromatic compounds BAYER AG (DE) 1990-11-28 EP disclosed
EP-0259798-A2 Electrical insulating oil composition NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-03-16 EP disclosed