SCHEMBL9065313

SCHEMBL9065313

O=C(O)c1cccc(-c2cc[c]cc2)c1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 1/20 0.49
HSD17B10 Q99714 1/20 0.43
FOLH1 Q04609 3/20 0.41
FABP3 P05413 1/20 0.41
FABP4 P15090 1/20 0.41
FABP5 Q01469 1/20 0.41
ALDH1A1 P00352 3/20 0.40
ALOX15 P16050 1/20 0.40
MYC P01106 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
BCAT2 O15382 1/20 0.39
LIG1 P18858 1/20 0.38
AKR1C3 P42330 1/20 0.37
CDC25B P30305 2/20 0.37
ATM Q13315 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL27621610 0.87 HNF4A (0.63) HNF4AHSD17B10FOLH1FABP3FABP4
SCHEMBL28567708 0.87 HNF4A (0.62) HNF4AHSD17B10FOLH1FABP3FABP4
SCHEMBL1362671 0.87 HNF4A (0.57) HNF4AHSD17B10FOLH1FABP3FABP4
Water SCHEMBL28005494 0.85 HNF4A (0.61) HNF4AHSD17B10FOLH1FABP3FABP4
Biphenyl SCHEMBL6227288 0.85 HNF4A (0.61) HNF4AHSD17B10FOLH1FABP3FABP4
SCHEMBL9550356 0.85 HNF4A (0.55) HNF4AHSD17B10FOLH1FABP3FABP4
SCHEMBL36146 0.85 HNF4A (0.66) HNF4AHSD17B10FOLH1FABP3FABP4
SCHEMBL29376910 0.85 HNF4A (0.66) HNF4AHSD17B10FOLH1FABP3FABP4
Water SCHEMBL7131144 0.84 HSD17B10 (0.56) HNF4AHSD17B10FOLH1ALDH1A1ALOX15
Bromide SCHEMBL8757513 0.83 HNF4A (0.63) HNF4AHSD17B10FOLH1FABP3FABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3819283-A1 METHOD FOR PRODUCING ORGANIC COMPOUND Unitika Ltd. (JP) 2021-05-12 EP disclosed
CN-1249161-C Casting compound based on thermosetting epoxy resin ABB RESEARCH LTD (CH) 2006-04-05 CN disclosed
EP-0462282-B1 POLYIMIDE MOLDING MITSUI TOATSU CHEMICALS (JP) 1996-06-26 EP disclosed
EP-0462282-A1 POLYIMIDE MOLDING MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-12-27 EP disclosed