SCHEMBL9065321

SCHEMBL9065321

CCOC(OCC)(C(=O)c1ccccc1)c1ccccc1.CCOC(OCC)(C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 4/20 0.66
SRC P12931 1/20 0.43
LMNA P02545 2/20 0.41
CES2 O00748 2/20 0.40
ALDH1A1 P00352 2/20 0.40
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
KMT2A Q03164 1/20 0.40
MAPT P10636 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
HIF1A Q16665 2/20 0.39
KCNN4 O15554 1/20 0.39
CYP2C19 P33261 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
POLB P06746 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
EDNRB P24530 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL36702 1.00 CES1 (0.66) CES1SRCLMNACES2ALDH1A1
SCHEMBL608102 0.94 CES1 (0.78) CES1SRCLMNACES2ALDH1A1
Acetophenone SCHEMBL27649666 0.94 CES1 (0.58) CES1SRCLMNAALDH1A1MEN1
SCHEMBL5598169 0.92 CES1 (0.75) CES1SRCLMNACES2ALDH1A1
SCHEMBL18790795 0.90 CES1 (0.54) CES1SRCLMNACES2ALDH1A1
SCHEMBL27936804 0.89 CES1 (0.61) CES1SRCLMNACES2ALDH1A1
SCHEMBL8633766 0.88 CES1 (0.53) CES1SRCLMNAALDH1A1MEN1
SCHEMBL9298990 0.88 CES1 (0.53) CES1LMNANPC1MAPTCYP3A4
SCHEMBL9860776 0.88 CES1 (0.64) CES1SRCLMNACES2ALDH1A1
SCHEMBL9475637 0.88 CES1 (0.55) CES1SRCLMNACES2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0366884-B1 Novel vinyl-terminated carbamylmethylated melamines, vinyl-terminated polyurethane/polyamide polymers and coating/adhesive compositions containing same CYTEC TECH CORP (US) 1996-01-03 EP disclosed
US-5359014-A Low temperature curing CYTEC TECHNOLOGY CORP. (US) 1994-10-25 US disclosed
EP-0366884-A2 Novel vinyl-terminated carbamylmethylated melamines, vinyl-terminated polyurethane/polyamide polymers and coating/adhesive compositions containing same CYTEC TECHNOLOGY CORP. (US) 1990-05-09 EP disclosed