Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL36702 | 0.88 | CES1 (0.66) | CES1LMNAMAPK1NPC1SMN1; SMN2 | |
| SCHEMBL9065321 | 0.88 | CES1 (0.66) | CES1LMNAMAPK1NPC1SMN1; SMN2 | |
| Acetophenone SCHEMBL27649666 | 0.82 | CES1 (0.58) | CES1MAOBLMNAL3MBTL1NPC1 | |
| SCHEMBL11482921 | 0.82 | CES1 (0.50) | CES1LMNAMAPK1L3MBTL1NPC1 | |
| SCHEMBL608102 | 0.82 | CES1 (0.78) | CES1LMNAL3MBTL1NPC1MAPT | |
| SCHEMBL21784939 | 0.80 | ALDH1A1 (0.50) | CES1PARP10LMNAMAPK1L3MBTL1 | |
| SCHEMBL5598169 | 0.80 | CES1 (0.75) | CES1LMNAL3MBTL1NPC1MAPT | |
| SCHEMBL18790795 | 0.79 | CES1 (0.54) | CES1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27936804 | 0.78 | CES1 (0.61) | CES1LMNAL3MBTL1NPC1MAPT | |
| SCHEMBL8633766 | 0.77 | CES1 (0.53) | CES1LMNAMAPK1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190602-A | PHOTOCHEMICAL SENSITIZERS BY REACTION OF SULFUROUS ACID ESTER OR THIONYL CHLORIDE AND A PRIMARY ALCOHOL | CIBA-GEIGY CORPORATION (US) | 1980-02-26 | — | — | US | disclosed |